SARS (GeneID: 6301) | Homo sapiens
Description:seryl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:10537]
Synonyms: SERS, SERRS
Other ID(s): ENSG00000031698, HGNC:10537
Protein Accession Numbers: NP_006504, ENST00000234677, NP_001317598, ENST00000234677.2
Statistics: ClinVar(2) gnomAD(307) COSMIC(158) dbSNP(6) PTM(39)
ClinVar Pathogenicity of Variations help

+Please click the name of species for the protein accession number used in the alignment.
+A * (asterisk) used as a pointer to positions of post translational modifications in human.
+Protein domains illustrated above belong to Homo sapiens (Human).
+ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene:
+If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000234677 You are here now! NP_001317598 NP_006504 You are here now!


insert_chartAmino Acid Conservation Percentage (Human versus Organisms with ClinVar and gnomAD Data)

import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Name filter_list Description filter_list Type filter_list Positions filter_list BitScore filter_list E-Value filter_list Clan filter_list
NO RESULT FOUND
Seryl_tRNA_N Seryl-tRNA synthetase N-terminal domain Domain 2-99 66.8 1.7e-18 CL0298
tRNA-synt_2b tRNA synthetase class II core domain (G, H, P, S and T) Domain 259-444 163.9 3.5e-48 CL0040

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
NEURODEVELOPMENTAL DISORDER WITH MICROCEPHALY, ATAXIA, AND SEIZURES N/A 0.639 0.414
NO RESULT FOUND
feedback