TET2 (GeneID: 54790) | Homo sapiens
Description:tet methylcytosine dioxygenase 2 [Source:HGNC Symbol;Acc:HGNC:25941]
Synonyms: KIAA1546, MDS
Other ID(s): HGNC:25941, ENSG00000168769
Protein Accession Numbers: ENST00000540549, NP_001120680, ENST00000380013, ENST00000540549.1, ENST00000305737, NP_060098
Statistics:

+Please click the name of species for the protein accession number used in the alignment.
+A * (asterisk) used as a pointer to positions of post translational modifications in human.
+Protein domains illustrated above belong to Homo sapiens (Human).
+ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene:
+If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
NP_001120680 NP_060098 You are here now!


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Name filter_list Description filter_list Type filter_list Positions filter_list BitScore filter_list E-Value filter_list Clan filter_list
NO RESULT FOUND
NO DOMAINS EXIST

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Primary Myelofibrosis Hemic and Lymphatic Diseases ; 0.499 0.586
Refractory anemias Hemic and Lymphatic Diseases ; 0.499 0.586
Refractory anaemia with excess blasts Hemic and Lymphatic Diseases ; 0.499 0.586
Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.499 0.586
Cytopenia N/A 0.499 0.586
Angioimmunoblastic Lymphadenopathy Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.499 0.586
Leukemia, Myelocytic, Acute Neoplasms ; 0.499 0.586
Leukemia, Myelomonocytic, Chronic Neoplasms ; Hemic and Lymphatic Diseases ; 0.499 0.586
Acute Promyelocytic Leukemia Neoplasms ; 0.499 0.586
Myelofibrosis N/A 0.499 0.586
Neoplasm Recurrence, Local Neoplasms ; Pathological Conditions, Signs and Symptoms ; 0.499 0.586
Polycythemia Vera Neoplasms ; Hemic and Lymphatic Diseases ; 0.499 0.586
Prostatic Neoplasms Neoplasms ; Male Urogenital Diseases ; 0.499 0.586
Sezary Syndrome Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.499 0.586
Thrombocythemia, Essential Hemic and Lymphatic Diseases ; 0.499 0.586
Peripheral T-Cell Lymphoma Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.499 0.586
Congenital anemia N/A 0.499 0.586
Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.499 0.586
secondary acute myeloid leukemia N/A 0.499 0.586
Malignant neoplasm of prostate Neoplasms ; Male Urogenital Diseases ; 0.499 0.586
Refractory anemia with ringed sideroblasts N/A 0.499 0.586
Chromophobe Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.499 0.586
Sarcomatoid Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.499 0.586
Collecting Duct Carcinoma of the Kidney Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.499 0.586
Acute myeloid leukemia with multilineage dysplasia N/A 0.499 0.586
Papillary Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.499 0.586
Hematopoetic Myelodysplasia Hemic and Lymphatic Diseases ; 0.499 0.586
MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases ; 0.499 0.586
NO RESULT FOUND
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