ldlCp (GeneID: 41870) | Drosophila melanogaster
Description:ldlCp-related protein [Source:FlyBase;Acc:FBgn0026634]
Synonyms: ldl-Cp, Cog2, Dmel_CG6177, CG6177, Dmel\CG6177
Other ID(s): FBgn0026634
Protein Accession Numbers: NP_524366
Statistics: ClinVar(6) gnomAD(609) COSMIC(245) dbSNP(18) PTM(35)
ClinVar Pathogenicity of Variations help

+Please click the name of species for the protein accession number used in the alignment.
+A * (asterisk) used as a pointer to positions of post translational modifications in human.
+Protein domains illustrated above belong to Homo sapiens (Human).
+ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene:
+If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000366669 You are here now! NP_001138508 NP_031383 You are here now!

insert_chartAmino Acid Conservation Percentage (Human versus Organisms with ClinVar and gnomAD Data)

import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Name filter_list Description filter_list Type filter_list Positions filter_list BitScore filter_list E-Value filter_list Clan filter_list
COG2 COG (conserved oligomeric Golgi) complex component, COG2 Family 15-146 147.8 1.8e-43 CL0295
DUF3510 Domain of unknown function (DUF3510) Family 574-699 141.9 1.3e-41 No_clan

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Congenital Disorders of Glycosylation Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Nutritional and Metabolic Diseases ; 0.785 0.172