MPO (GeneID: 4353) | Homo sapiens
Description: myeloperoxidase [Source:HGNC Symbol;Acc:HGNC:7218]
Synonyms:
Other ID(s): ENSG00000005381, HGNC:7218
Protein Accession Numbers: NP_000241, ENST00000225275.3, ENST00000577220, ENST00000225275, ENST00000340482
Statistics: ClinVar(22) COSMIC(341) PTM(11)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000225275 You are here now! ENST00000340482 ENST00000577220 NP_000241 You are here now!


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF03098 An_peroxidase Animal haem peroxidase 173-718 CL0617 Peroxidase Homo sapiens

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Alcoholic Intoxication Chemically-Induced Disorders ; Mental Disorders ; 0.435 0.931
Alloxan Diabetes Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.435 0.931
Alzheimer's Disease Nervous System Diseases ; Mental Disorders ; 0.435 0.931
Anoxemia Pathological Conditions, Signs and Symptoms ; 0.435 0.931
Anoxia Pathological Conditions, Signs and Symptoms ; 0.435 0.931
Arthritis, Adjuvant-Induced Musculoskeletal Diseases ; 0.435 0.931
Rheumatoid Arthritis Musculoskeletal Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ; 0.435 0.931
Cholestasis, Extrahepatic Digestive System Diseases ; 0.435 0.931
Malignant neoplasm of urinary bladder Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.435 0.931
Bladder Neoplasm Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.435 0.931
Brain Diseases Nervous System Diseases ; 0.435 0.931
Burn injury Wounds and Injuries ; 0.435 0.931
Cardiomyopathy, Dilated Cardiovascular Diseases ; 0.435 0.931
Cardiovascular Diseases Cardiovascular Diseases ; 0.435 0.931
Brain Ischemia Nervous System Diseases ; Cardiovascular Diseases ; 0.435 0.931
Colitis Digestive System Diseases ; 0.435 0.931
Ulcerative Colitis Digestive System Diseases ; 0.435 0.931
Presenile dementia Nervous System Diseases ; Mental Disorders ; 0.435 0.931
Involutional Depression Mental Disorders ; 0.435 0.931
Drug Eruptions Skin and Connective Tissue Diseases ; Immune System Diseases ; Chemically-Induced Disorders ; 0.435 0.931
Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.435 0.931
Inflammation Pathological Conditions, Signs and Symptoms ; 0.435 0.931
Keratosis Skin and Connective Tissue Diseases ; 0.435 0.931
Keratosis Blennorrhagica Skin and Connective Tissue Diseases ; 0.435 0.931
Kidney Diseases Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.435 0.931
Kidney Failure, Acute Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.435 0.931
Liver Cirrhosis, Alcoholic Digestive System Diseases ; Chemically-Induced Disorders ; 0.435 0.931
Lung diseases Respiratory Tract Diseases ; 0.435 0.931
Lung Neoplasms Neoplasms ; Respiratory Tract Diseases ; 0.435 0.931
Occupational Diseases Occupational Diseases ; 0.435 0.931
Pancreatitis Digestive System Diseases ; 0.435 0.931
Precancerous Conditions Neoplasms ; 0.435 0.931
Prostatic Neoplasms Neoplasms ; Male Urogenital Diseases ; 0.435 0.931
Reperfusion Injury Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ; 0.435 0.931
Shock, Hemorrhagic Pathological Conditions, Signs and Symptoms ; 0.435 0.931
Streptozotocin Diabetes Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.435 0.931
Infection by Trichuris trichiura Parasitic Diseases ; 0.435 0.931
Urticaria Skin and Connective Tissue Diseases ; Immune System Diseases ; 0.435 0.931
Injury wounds Wounds and Injuries ; 0.435 0.931
Wounds and Injuries Wounds and Injuries ; 0.435 0.931
Encephalopathies Nervous System Diseases ; 0.435 0.931
Injuries, Acute Brain Nervous System Diseases ; Wounds and Injuries ; 0.435 0.931
Keratoma Skin and Connective Tissue Diseases ; 0.435 0.931
Hypoxia Pathological Conditions, Signs and Symptoms ; 0.435 0.931
Malignant neoplasm of lung Neoplasms ; Respiratory Tract Diseases ; 0.435 0.931
Conduction disorder of the heart Cardiovascular Diseases ; 0.435 0.931
Brain Injuries Nervous System Diseases ; Wounds and Injuries ; 0.435 0.931
Brain Lacerations Nervous System Diseases ; Wounds and Injuries ; 0.435 0.931
Familial Alzheimer Disease (FAD) Nervous System Diseases ; Mental Disorders ; 0.435 0.931
Condition, Preneoplastic Neoplasms ; 0.435 0.931
Malignant neoplasm of prostate Neoplasms ; Male Urogenital Diseases ; 0.435 0.931
Myeloperoxidase Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Nutritional and Metabolic Diseases ; 0.435 0.931
Morbilliform Drug Reaction Skin and Connective Tissue Diseases ; Immune System Diseases ; Chemically-Induced Disorders ; 0.435 0.931
Brain Injuries, Focal Nervous System Diseases ; Wounds and Injuries ; 0.435 0.931
Alzheimer Disease, Late Onset Nervous System Diseases ; Mental Disorders ; 0.435 0.931
Acute Confusional Senile Dementia Nervous System Diseases ; Mental Disorders ; 0.435 0.931
Hypoxemia Pathological Conditions, Signs and Symptoms ; 0.435 0.931
Alzheimer's Disease, Focal Onset Nervous System Diseases ; Mental Disorders ; 0.435 0.931
Alzheimer Disease, Early Onset Nervous System Diseases ; Mental Disorders ; 0.435 0.931
Cerebral Ischemia Nervous System Diseases ; Cardiovascular Diseases ; 0.435 0.931
Arthritis, Collagen-Induced Musculoskeletal Diseases ; 0.435 0.931
Arthritis, Experimental Musculoskeletal Diseases ; 0.435 0.931
Major Depressive Disorder Mental Disorders ; 0.435 0.931
Colorectal Cancer Neoplasms ; Digestive System Diseases ; 0.435 0.931
Acute Kidney Insufficiency Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.435 0.931
Involutional paraphrenia Mental Disorders ; 0.435 0.931
Psychosis, Involutional Mental Disorders ; 0.435 0.931
Liver carcinoma Neoplasms ; Digestive System Diseases ; 0.435 0.931
Acute kidney injury Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.435 0.931
Traumatic injury Wounds and Injuries ; 0.435 0.931
Research-Related Injuries Wounds and Injuries ; 0.435 0.931
NO RESULT FOUND
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