IGF2 (GeneID: 3481) | Homo sapiens
Description: insulin like growth factor 2 [Source:NCBI gene;Acc:3481]
Synonyms: PP9974, C11orf43, IGF-II, GRDF
Other ID(s): HGNC:5466, ENSG00000284779, ENSG00000167244
Protein Accession Numbers: ENST00000418738, ENST00000381395, NP_001121070, ENST00000381389, ENST00000434045.2, ENST00000416167, NP_001278791, ENST00000381392, NP_001007140, ENST00000300632, ENST00000434045, ENST00000381406, NP_001278790, ENST00000381389.1, NP_000603
Statistics: ClinVar(84) gnomAD(875) COSMIC(963) PTM(2)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000300632 You are here now! ENST00000381389 You are here now! ENST00000381392 ENST00000381395 You are here now! ENST00000381406 ENST00000416167 You are here now! ENST00000418738 You are here now! ENST00000434045 NP_000603 You are here now! NP_001007140 You are here now! NP_001121070 NP_001278790 You are here now! NP_001278791 You are here now!


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF00049 Insulin Insulin/IGF/Relaxin family 54-84 CL0239 Insulin Homo sapiens
PF00049 Insulin Insulin/IGF/Relaxin family 30-62 CL0239 Insulin Homo sapiens
PF08365 IGF2_C Insulin-like growth factor II E-peptide 112-166 Homo sapiens

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Spontaneous abortion Female Urogenital Diseases and Pregnancy Complications ; 0.399 0.828
Abortion, Tubal Female Urogenital Diseases and Pregnancy Complications ; 0.399 0.828
Alzheimer's Disease Nervous System Diseases ; Mental Disorders ; 0.399 0.828
Anemia Hemic and Lymphatic Diseases ; 0.399 0.828
Atherosclerosis Cardiovascular Diseases ; 0.399 0.828
Autistic Disorder Mental Disorders ; 0.399 0.828
Beckwith-Wiedemann Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.399 0.828
Bone Diseases, Developmental Musculoskeletal Diseases ; 0.399 0.828
Malignant tumor of colon Neoplasms ; Digestive System Diseases ; 0.399 0.828
Cognition Disorders Mental Disorders ; 0.399 0.828
Colonic Neoplasms Neoplasms ; Digestive System Diseases ; 0.399 0.828
Colorectal Carcinoma Neoplasms ; Digestive System Diseases ; 0.399 0.828
Colorectal Neoplasms Neoplasms ; Digestive System Diseases ; 0.399 0.828
Presenile dementia Nervous System Diseases ; Mental Disorders ; 0.399 0.828
Fetal Growth Retardation Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Pathological Conditions, Signs and Symptoms ; 0.399 0.828
Growth Disorders Pathological Conditions, Signs and Symptoms ; 0.399 0.828
Diaphragmatic Hernia Pathological Conditions, Signs and Symptoms ; 0.399 0.828
Polyhydramnios Female Urogenital Diseases and Pregnancy Complications ; 0.399 0.828
Hypoglycemia Nutritional and Metabolic Diseases ; 0.399 0.828
Liver neoplasms Neoplasms ; Digestive System Diseases ; 0.399 0.828
Memory Disorders Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ; 0.399 0.828
Nephroblastoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.399 0.828
Nerve Degeneration Pathological Conditions, Signs and Symptoms ; 0.399 0.828
Obesity Nutritional and Metabolic Diseases ; Pathological Conditions, Signs and Symptoms ; 0.399 0.828
Parkinson Disease Nervous System Diseases ; 0.399 0.828
Placenta Disorders Female Urogenital Diseases and Pregnancy Complications ; 0.399 0.828
Precancerous Conditions Neoplasms ; 0.399 0.828
Rhabdomyosarcoma Neoplasms ; 0.399 0.828
Schizophrenia Mental Disorders ; 0.399 0.828
Russell-Silver syndrome Musculoskeletal Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.399 0.828
Hepatoblastoma Neoplasms ; 0.399 0.828
Adrenocortical carcinoma Neoplasms ; Endocrine System Diseases ; 0.399 0.828
Memory impairment Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ; 0.399 0.828
Fasting Hypoglycemia Nutritional and Metabolic Diseases ; 0.399 0.828
Reactive hypoglycemia Nutritional and Metabolic Diseases ; 0.399 0.828
Familial Alzheimer Disease (FAD) Nervous System Diseases ; Mental Disorders ; 0.399 0.828
Condition, Preneoplastic Neoplasms ; 0.399 0.828
Congenital hemihypertrophy N/A 0.399 0.828
Malignant neoplasm of liver Neoplasms ; Digestive System Diseases ; 0.399 0.828
Alzheimer Disease, Late Onset Nervous System Diseases ; Mental Disorders ; 0.399 0.828
Acute Confusional Senile Dementia Nervous System Diseases ; Mental Disorders ; 0.399 0.828
prenatal alcohol exposure N/A 0.399 0.828
Alzheimer's Disease, Focal Onset Nervous System Diseases ; Mental Disorders ; 0.399 0.828
Alzheimer Disease, Early Onset Nervous System Diseases ; Mental Disorders ; 0.399 0.828
Age-Related Memory Disorders Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ; 0.399 0.828
Memory Disorder, Semantic Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ; 0.399 0.828
Memory Disorder, Spatial Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ; 0.399 0.828
Memory Loss Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ; 0.399 0.828
Lewy Body Disease Nervous System Diseases ; Mental Disorders ; 0.399 0.828
Colorectal Cancer Neoplasms ; Digestive System Diseases ; 0.399 0.828
Atherogenesis Cardiovascular Diseases ; 0.399 0.828
HEMIHYPERPLASIA, ISOLATED Pathological Conditions, Signs and Symptoms ; 0.399 0.828
Liver carcinoma Neoplasms ; Digestive System Diseases ; 0.399 0.828
Bilateral Wilms Tumor Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.399 0.828
Intellectual Disability Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ; Mental Disorders ; 0.399 0.828
GROWTH RESTRICTION, SEVERE, WITH DISTINCTIVE FACIES N/A 0.399 0.828
NO RESULT FOUND
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