Description: | potassium voltage-gated channel subfamily H member 2 [Source:HGNC Symbol;Acc:HGNC:6251] |
Synonyms: | QT2, HERG, ERG-1, Kv11.1, H-ERG, SQT1, HERG1, ERG1 |
Other ID(s): | ENSG00000055118, HGNC:6251 |
Protein Accession Numbers: | ENST00000430723, ENST00000262186.5, NP_001191727, ENST00000392968, ENST00000262186, NP_742054, NP_000229, ENST00000330883, NP_742053 |
Statistics: | ClinVar(1455) gnomAD(1078) COSMIC(475) PTM(22) |
∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000262186 You are here now!
ENST00000330883
ENST00000392968
ENST00000430723
NP_000229 You are here now!
NP_001191727
NP_742053
NP_742054
Pfam Domain filter_list | Domain Name filter_list | Description filter_list | Positions filter_list | Clan filter_list | Clan Name filter_list | Organism filter_list |
---|---|---|---|---|---|---|
NO RESULT FOUND | ||||||
PF00027 | cNMP_binding | Cyclic nucleotide-binding domain | 760-845 | CL0029 | Cupin | Homo sapiens |
PF00520 | Ion_trans | Ion transport protein | 407-671 | CL0030 | Ion_channel | Homo sapiens |
PF13426 | PAS_9 | PAS domain | 29-132 | CL0183 | PAS_Fold | Homo sapiens |
Disease Name filter_list | Disease Category filter_list | DSI* filter_list | DPI** filter_list | ||
---|---|---|---|---|---|
Cardiac Arrhythmia | Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ; | 0.543 | 0.586 | ||
Malignant Neoplasms | Neoplasms ; | 0.543 | 0.586 | ||
Malignant tumor of colon | Neoplasms ; Digestive System Diseases ; | 0.543 | 0.586 | ||
Neoplastic Cell Transformation | Neoplasms ; Pathological Conditions, Signs and Symptoms ; | 0.543 | 0.586 | ||
Colonic Neoplasms | Neoplasms ; Digestive System Diseases ; | 0.543 | 0.586 | ||
Long QT Syndrome | Cardiovascular Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Pathological Conditions, Signs and Symptoms ; | 0.543 | 0.586 | ||
Muscular Atrophy | Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; | 0.543 | 0.586 | ||
Neoplasms | Neoplasms ; | 0.543 | 0.586 | ||
Psychotic Disorders | Mental Disorders ; | 0.543 | 0.586 | ||
Romano-Ward Syndrome | Cardiovascular Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Pathological Conditions, Signs and Symptoms ; | 0.543 | 0.586 | ||
Schizophrenia | Mental Disorders ; | 0.543 | 0.586 | ||
Torsades de Pointes | Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ; | 0.543 | 0.586 | ||
Benign Neoplasm | Neoplasms ; | 0.543 | 0.586 | ||
Neurogenic Muscular Atrophy | Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; | 0.543 | 0.586 | ||
Nonorganic psychosis | N/A | 0.543 | 0.586 | ||
Brugada Syndrome (disorder) | Cardiovascular Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; | 0.543 | 0.586 | ||
Short QT Syndrome 1 | Cardiovascular Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Pathological Conditions, Signs and Symptoms ; | 0.543 | 0.586 | ||
Long Qt Syndrome 2 | Cardiovascular Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Pathological Conditions, Signs and Symptoms ; | 0.543 | 0.586 | ||
LONG QT SYNDROME 2/3, DIGENIC | N/A | 0.543 | 0.586 | ||
LONG QT SYNDROME 1/2, DIGENIC (disorder) | N/A | 0.543 | 0.586 | ||
LONG QT SYNDROME 2/5, DIGENIC (disorder) | N/A | 0.543 | 0.586 | ||
LONG QT SYNDROME 2/9, DIGENIC | N/A | 0.543 | 0.586 | ||
LONG QT SYNDROME 2, ACQUIRED, SUSCEPTIBILITY TO | N/A | 0.543 | 0.586 | ||
NO RESULT FOUND |