Sgk1 (GeneID: 20393) | Mus musculus
Description: serum/glucocorticoid regulated kinase 1 [Source:MGI Symbol;Acc:MGI:1340062]
Synonyms: Sgk
Other ID(s): MGI:1340062, ENSMUSG00000019970
Protein Accession Numbers: NP_001155321, NP_001155317, NP_035491, NP_001155320, NP_001155322, NP_001155319
Statistics: ClinVar(2) gnomAD(375) COSMIC(538) PTM(22)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000237305 ENST00000367857 ENST00000367858 ENST00000413996 ENST00000460769 ENST00000461976 ENST00000475719 ENST00000524929 ENST00000528577 You are here now! ENST00000533224 NP_001137148 NP_001137149 You are here now! NP_001137150 NP_001278924 NP_005618


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF00433 Pkinase_C Protein kinase C terminal domain 376-423 Homo sapiens
PF00069 Pkinase Protein kinase domain 98-355 CL0016 PKinase Homo sapiens

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Carcinoma Neoplasms ; 0.53 0.621
Diabetic Neuropathies Nervous System Diseases ; Endocrine System Diseases ; 0.53 0.621
Leukemia, Myelocytic, Acute Neoplasms ; 0.53 0.621
Animal Mammary Neoplasms Neoplasms ; Animal Diseases ; 0.53 0.621
Mammary Neoplasms, Experimental Neoplasms ; 0.53 0.621
Acute Myeloid Leukemia, M1 Neoplasms ; 0.53 0.621
Unipolar Depression Mental Disorders ; 0.53 0.621
Uremia Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.53 0.621
Diffuse Large B-Cell Lymphoma Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.53 0.621
Anaplastic carcinoma Neoplasms ; 0.53 0.621
Carcinoma, Spindle-Cell Neoplasms ; 0.53 0.621
Undifferentiated carcinoma Neoplasms ; 0.53 0.621
Carcinomatosis Neoplasms ; 0.53 0.621
Symmetric Diabetic Proximal Motor Neuropathy Nervous System Diseases ; Endocrine System Diseases ; 0.53 0.621
Asymmetric Diabetic Proximal Motor Neuropathy Nervous System Diseases ; Endocrine System Diseases ; 0.53 0.621
Diabetic Mononeuropathy Nervous System Diseases ; Endocrine System Diseases ; 0.53 0.621
Diabetic Polyneuropathies Nervous System Diseases ; Endocrine System Diseases ; 0.53 0.621
Diabetic Amyotrophy Nervous System Diseases ; Endocrine System Diseases ; 0.53 0.621
Diabetic Autonomic Neuropathy Nervous System Diseases ; Endocrine System Diseases ; 0.53 0.621
Diabetic Asymmetric Polyneuropathy Nervous System Diseases ; Endocrine System Diseases ; 0.53 0.621
Diabetic Neuralgia Nervous System Diseases ; Endocrine System Diseases ; 0.53 0.621
Mammary Carcinoma, Animal Neoplasms ; Animal Diseases ; 0.53 0.621
Major Depressive Disorder Mental Disorders ; 0.53 0.621
Acute Myeloid Leukemia (AML-M2) Neoplasms ; 0.53 0.621
NO RESULT FOUND
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