DAPK1 (GeneID: 1612) | Homo sapiens
Description: death associated protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:2674]
Synonyms: DAPK, ROCO3
Other ID(s): HGNC:2674, ENSG00000196730
Protein Accession Numbers: ENST00000469640, NP_001275659, ENST00000489291, ENST00000408954, NP_004929, NP_001275658, ENST00000472284, ENST00000358077, NP_001275660, ENST00000491893
Statistics: ClinVar(72) gnomAD(2424) COSMIC(2758) PTM(36)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000358077 You are here now! ENST00000408954 You are here now! ENST00000469640 ENST00000472284 You are here now! ENST00000489291 ENST00000491893 NP_001275658 You are here now! NP_001275659 You are here now! NP_001275660 You are here now! NP_004929 You are here now!


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF00531 Death Death domain 1310-1396 CL0041 Death Homo sapiens
PF00023 Ank Ankyrin repeat 444-476 CL0465 Ank Homo sapiens
PF00023 Ank Ankyrin repeat 609-641 CL0465 Ank Homo sapiens
PF00023 Ank Ankyrin repeat 477-509 CL0465 Ank Homo sapiens
PF00023 Ank Ankyrin repeat 576-608 CL0465 Ank Homo sapiens
PF00023 Ank Ankyrin repeat 510-542 CL0465 Ank Homo sapiens
PF00069 Pkinase Protein kinase domain 13-275 CL0016 PKinase Homo sapiens

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Adenocarcinoma Neoplasms ; 0.513 0.655
Brain Neoplasms Neoplasms ; Nervous System Diseases ; 0.513 0.655
Non-Small Cell Lung Carcinoma Neoplasms ; Respiratory Tract Diseases ; 0.513 0.655
Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.513 0.655
Carcinoma, Transitional Cell Neoplasms ; 0.513 0.655
Conjunctival Diseases Eye Diseases ; 0.513 0.655
Adenoid Cystic Carcinoma Neoplasms ; 0.513 0.655
Leukemia, Myelocytic, Acute Neoplasms ; 0.513 0.655
Lung Neoplasms Neoplasms ; Respiratory Tract Diseases ; 0.513 0.655
Acute Myeloid Leukemia, M1 Neoplasms ; 0.513 0.655
Neoplasm Metastasis Neoplasms ; Pathological Conditions, Signs and Symptoms ; 0.513 0.655
Peripheral Neuropathy Nervous System Diseases ; 0.513 0.655
Respiratory Tract Diseases Respiratory Tract Diseases ; 0.513 0.655
Salivary Gland Neoplasms Neoplasms ; Stomatognathic Diseases ; 0.513 0.655
Neoplasms, Second Primary Neoplasms ; 0.513 0.655
Neoplasms, Therapy-Associated Neoplasms ; 0.513 0.655
Juvenile-Onset Still Disease Musculoskeletal Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ; 0.513 0.655
Malignant neoplasm of brain Neoplasms ; Nervous System Diseases ; 0.513 0.655
Adenocarcinoma, Basal Cell Neoplasms ; 0.513 0.655
Adenocarcinoma, Oxyphilic Neoplasms ; 0.513 0.655
Carcinoma, Cribriform Neoplasms ; 0.513 0.655
Carcinoma, Granular Cell Neoplasms ; 0.513 0.655
Adenocarcinoma, Tubular Neoplasms ; 0.513 0.655
Malignant neoplasm of salivary gland Neoplasms ; Stomatognathic Diseases ; 0.513 0.655
Malignant neoplasm of lung Neoplasms ; Respiratory Tract Diseases ; 0.513 0.655
Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.513 0.655
Benign neoplasm of brain, unspecified Neoplasms ; Nervous System Diseases ; 0.513 0.655
Brain Tumor, Primary Neoplasms ; Nervous System Diseases ; 0.513 0.655
Recurrent Brain Neoplasm Neoplasms ; Nervous System Diseases ; 0.513 0.655
Primary malignant neoplasm of brain Neoplasms ; Nervous System Diseases ; 0.513 0.655
Treatment related secondary malignancy Neoplasms ; 0.513 0.655
Chromophobe Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.513 0.655
Sarcomatoid Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.513 0.655
Collecting Duct Carcinoma of the Kidney Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.513 0.655
Papillary Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.513 0.655
Neoplasms, Intracranial Neoplasms ; Nervous System Diseases ; 0.513 0.655
Acute Myeloid Leukemia (AML-M2) Neoplasms ; 0.513 0.655
Hematopoetic Myelodysplasia Hemic and Lymphatic Diseases ; 0.513 0.655
MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases ; 0.513 0.655
Juvenile arthritis Musculoskeletal Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ; 0.513 0.655
Juvenile psoriatic arthritis Musculoskeletal Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ; 0.513 0.655
NO RESULT FOUND
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