CASP7 (GeneID: 840) | Homo sapiens
Description: caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508]
Synonyms: LICE2, CASP-7, ICE-LAP3, MCH3, CMH-1
Other ID(s): HGNC:1508, ENSG00000165806
Protein Accession Numbers: NP_001218, ENST00000369331, NP_203124, ENST00000369315, NP_001253986, ENST00000452490, NP_203126, ENST00000369321, NP_001307840, ENST00000345633, NP_001253985, ENST00000429617, NP_203125, ENST00000369318, NP_001253987
Statistics: ClinVar(2) PTM(21)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000345633 ENST00000369315 ENST00000369318 ENST00000369321 ENST00000369331 ENST00000429617 ENST00000452490 NP_001218 NP_001253985 NP_001253986 NP_001253987 NP_001307840 You are here now! NP_203124 NP_203125 NP_203126


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF00656 Peptidase_C14 Caspase domain 67-300 CL0093 Peptidase_CD Homo sapiens

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Malignant neoplasm of breast Neoplasms ; Skin and Connective Tissue Diseases ; 0.611 0.586
Leukemia, Myelocytic, Acute Neoplasms ; 0.611 0.586
Liver Cirrhosis, Experimental Digestive System Diseases ; 0.611 0.586
Acute Myeloid Leukemia, M1 Neoplasms ; 0.611 0.586
Myocardial Reperfusion Injury Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ; 0.611 0.586
Vitiligo Skin and Connective Tissue Diseases ; 0.611 0.586
Breast Carcinoma Neoplasms ; Skin and Connective Tissue Diseases ; 0.611 0.586
Mammary Neoplasms, Human Neoplasms ; Skin and Connective Tissue Diseases ; 0.611 0.586
Mammary Neoplasms Neoplasms ; Skin and Connective Tissue Diseases ; 0.611 0.586
Acute Myeloid Leukemia (AML-M2) Neoplasms ; 0.611 0.586
NO RESULT FOUND
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