DPYSL2 (GeneID: 1808) | Homo sapiens
Description: dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc:HGNC:3014]
Synonyms: N2A3, DRP-2, CRMP-2, LIP-2, DHPRP2, ULIP2, DRP2, CRMP2
Other ID(s): ENSG00000092964, HGNC:3014
Protein Accession Numbers: NP_001184222, ENST00000493789, NP_001377, ENST00000523027, ENST00000311151, NP_001231533, ENST00000521913
Statistics: ClinVar(11) gnomAD(343) COSMIC(317) PTM(51)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000311151 You are here now! ENST00000493789 ENST00000521913 ENST00000523027 NP_001184222 NP_001231533 NP_001377 You are here now!


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF01979 Amidohydro_1 Amidohydrolase family 64-453 CL0034 Amidohydrolase Homo sapiens

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Alcoholic Intoxication, Chronic Chemically-Induced Disorders ; Mental Disorders ; 0.63 0.517
Alzheimer's Disease Nervous System Diseases ; Mental Disorders ; 0.63 0.517
Bipolar Disorder Mental Disorders ; 0.63 0.517
Delusional disorder Mental Disorders ; 0.63 0.517
Presenile dementia Nervous System Diseases ; Mental Disorders ; 0.63 0.517
Mental Depression Behavior and Behavior Mechanisms ; 0.63 0.517
Depressive disorder Mental Disorders ; 0.63 0.517
Degenerative polyarthritis Musculoskeletal Diseases ; 0.63 0.517
Paranoid Schizophrenia Mental Disorders ; 0.63 0.517
Osteoarthrosis Deformans Musculoskeletal Diseases ; 0.63 0.517
Familial Alzheimer Disease (FAD) Nervous System Diseases ; Mental Disorders ; 0.63 0.517
Alzheimer Disease, Late Onset Nervous System Diseases ; Mental Disorders ; 0.63 0.517
Acute Confusional Senile Dementia Nervous System Diseases ; Mental Disorders ; 0.63 0.517
Alzheimer's Disease, Focal Onset Nervous System Diseases ; Mental Disorders ; 0.63 0.517
Alzheimer Disease, Early Onset Nervous System Diseases ; Mental Disorders ; 0.63 0.517
Colorectal Cancer Neoplasms ; Digestive System Diseases ; 0.63 0.517
NO RESULT FOUND
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