Hgf (GeneID: 15234) | Mus musculus
Description: hepatocyte growth factor [Source:MGI Symbol;Acc:MGI:96079]
Synonyms: NK1, C230052L06Rik, SF, HGF/SF, NK2, F/HGF
Other ID(s): ENSMUSG00000028864, MGI:96079
Protein Accession Numbers: NP_001276390, NP_001276387, XP_036020713, NP_001276389, NP_034557, NP_001276388
Statistics: ClinVar(46) gnomAD(541) COSMIC(965) PTM(1)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000222390 You are here now! ENST00000354224 ENST00000412881 ENST00000421558 ENST00000423064 ENST00000444829 ENST00000453018 ENST00000453411 ENST00000457544 NP_000592 You are here now! NP_001010931 NP_001010932 NP_001010933 NP_001010934


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF00024 PAN_1 PAN domain 40-124 CL0168 PAN Homo sapiens
PF00051 Kringle Kringle domain 211-288 CL0602 Kringle Homo sapiens
PF00051 Kringle Kringle domain 305-383 CL0602 Kringle Homo sapiens
PF00051 Kringle Kringle domain 128-206 CL0602 Kringle Homo sapiens
PF00051 Kringle Kringle domain 391-469 CL0602 Kringle Homo sapiens
PF00089 Trypsin Trypsin 495-716 CL0124 Peptidase_PA Homo sapiens

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Astrocytoma Neoplasms ; 0.394 0.793
Barrett Esophagus Neoplasms ; Digestive System Diseases ; 0.394 0.793
Squamous cell carcinoma Neoplasms ; 0.394 0.793
Diabetic Neuropathies Nervous System Diseases ; Endocrine System Diseases ; 0.394 0.793
Hepatitis, Chronic Digestive System Diseases ; 0.394 0.793
Hepatoma, Morris Neoplasms ; Digestive System Diseases ; 0.394 0.793
Hepatoma, Novikoff Neoplasms ; Digestive System Diseases ; 0.394 0.793
Leukemia, Myelocytic, Acute Neoplasms ; 0.394 0.793
Liver Cirrhosis Digestive System Diseases ; 0.394 0.793
Liver Cirrhosis, Experimental Digestive System Diseases ; 0.394 0.793
Liver neoplasms Neoplasms ; Digestive System Diseases ; 0.394 0.793
Liver Neoplasms, Experimental Neoplasms ; Digestive System Diseases ; 0.394 0.793
Acute Myeloid Leukemia, M1 Neoplasms ; 0.394 0.793
Neoplasm Invasiveness Neoplasms ; Pathological Conditions, Signs and Symptoms ; 0.394 0.793
Neoplasm Metastasis Neoplasms ; Pathological Conditions, Signs and Symptoms ; 0.394 0.793
Neoplasms, Experimental Neoplasms ; 0.394 0.793
Neuroblastoma Neoplasms ; 0.394 0.793
Pain Pathological Conditions, Signs and Symptoms ; 0.394 0.793
Pancreatitis Digestive System Diseases ; 0.394 0.793
Parkinson Disease Nervous System Diseases ; 0.394 0.793
Cardiomyopathies, Primary Cardiovascular Diseases ; 0.394 0.793
Pulmonary Fibrosis Respiratory Tract Diseases ; 0.394 0.793
Reperfusion Injury Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ; 0.394 0.793
Myocardial Diseases, Secondary Cardiovascular Diseases ; 0.394 0.793
Thrombosis Cardiovascular Diseases ; 0.394 0.793
Vascular Diseases Cardiovascular Diseases ; 0.394 0.793
Wounds, Penetrating Wounds and Injuries ; 0.394 0.793
Hamman-Rich syndrome Respiratory Tract Diseases ; 0.394 0.793
Experimental Hepatoma Neoplasms ; Digestive System Diseases ; 0.394 0.793
Thrombus Cardiovascular Diseases ; 0.394 0.793
Chronic Persistent Hepatitis Digestive System Diseases ; 0.394 0.793
Myocardial Ischemia Cardiovascular Diseases ; 0.394 0.793
Liver Failure, Acute Digestive System Diseases ; 0.394 0.793
Subependymal Giant Cell Astrocytoma Neoplasms ; 0.394 0.793
Pain, Burning Pathological Conditions, Signs and Symptoms ; 0.394 0.793
Ache Pathological Conditions, Signs and Symptoms ; 0.394 0.793
Radiating pain Pathological Conditions, Signs and Symptoms ; 0.394 0.793
Fibrosis, Liver Digestive System Diseases ; 0.394 0.793
Symmetric Diabetic Proximal Motor Neuropathy Nervous System Diseases ; Endocrine System Diseases ; 0.394 0.793
Asymmetric Diabetic Proximal Motor Neuropathy Nervous System Diseases ; Endocrine System Diseases ; 0.394 0.793
Diabetic Mononeuropathy Nervous System Diseases ; Endocrine System Diseases ; 0.394 0.793
Diabetic Polyneuropathies Nervous System Diseases ; Endocrine System Diseases ; 0.394 0.793
Diabetic Amyotrophy Nervous System Diseases ; Endocrine System Diseases ; 0.394 0.793
Diabetic Autonomic Neuropathy Nervous System Diseases ; Endocrine System Diseases ; 0.394 0.793
Juvenile Pilocytic Astrocytoma Neoplasms ; 0.394 0.793
Diffuse Astrocytoma Neoplasms ; 0.394 0.793
Anaplastic astrocytoma Neoplasms ; 0.394 0.793
Protoplasmic astrocytoma Neoplasms ; 0.394 0.793
Gemistocytic astrocytoma Neoplasms ; 0.394 0.793
Fibrillary Astrocytoma Neoplasms ; 0.394 0.793
Pilocytic Astrocytoma Neoplasms ; 0.394 0.793
Childhood Cerebral Astrocytoma Neoplasms ; 0.394 0.793
Malignant neoplasm of liver Neoplasms ; Digestive System Diseases ; 0.394 0.793
Malignant mesothelioma Neoplasms ; Respiratory Tract Diseases ; 0.394 0.793
Diabetic Asymmetric Polyneuropathy Nervous System Diseases ; Endocrine System Diseases ; 0.394 0.793
Pain, Splitting Pathological Conditions, Signs and Symptoms ; 0.394 0.793
Pain, Crushing Pathological Conditions, Signs and Symptoms ; 0.394 0.793
Chronic active hepatitis Digestive System Diseases ; 0.394 0.793
Cryptogenic Chronic Hepatitis Digestive System Diseases ; 0.394 0.793
Mixed oligoastrocytoma Neoplasms ; 0.394 0.793
Cerebral Astrocytoma Neoplasms ; 0.394 0.793
Intracranial Astrocytoma Neoplasms ; 0.394 0.793
Diabetic Neuralgia Nervous System Diseases ; Endocrine System Diseases ; 0.394 0.793
Pain, Migratory Pathological Conditions, Signs and Symptoms ; 0.394 0.793
Suffering, Physical Pathological Conditions, Signs and Symptoms ; 0.394 0.793
Cardiomyopathies Cardiovascular Diseases ; 0.394 0.793
Polyomavirus Infections Virus Diseases ; 0.394 0.793
Barrett Epithelium Neoplasms ; Digestive System Diseases ; 0.394 0.793
Grade I Astrocytoma Neoplasms ; 0.394 0.793
DEAFNESS, AUTOSOMAL RECESSIVE 39 (disorder) Otorhinolaryngologic Diseases ; Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.394 0.793
DEAFNESS, AUTOSOMAL RECESSIVE (disorder) Otorhinolaryngologic Diseases ; Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.394 0.793
Copper-Overload Cirrhosis Digestive System Diseases ; Nervous System Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Nutritional and Metabolic Diseases ; 0.394 0.793
Acute Myeloid Leukemia (AML-M2) Neoplasms ; 0.394 0.793
Liver carcinoma Neoplasms ; Digestive System Diseases ; 0.394 0.793
NO RESULT FOUND
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