wt1a (GeneID: 30245) | Danio rerio
Description: wilms tumor 1a [Source:ZFIN;Acc:ZDB-GENE-980526-558]
Synonyms: wt1, zwt1
Other ID(s): ZDB-GENE-980526-558, ENSDARG00000031420
Protein Accession Numbers: NP_571121
Statistics: ClinVar(617)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000332351 ENST00000379077 ENST00000379079 ENST00000448076 ENST00000452863 ENST00000526685 ENST00000527775 ENST00000527882 ENST00000530998 NP_000369 NP_001185480 NP_001185481 NP_001354783 NP_077742 NP_077744 You are here now!


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
NO DOMAINS EXIST

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Aniridia Eye Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.444 0.69
Malignant neoplasm of breast Neoplasms ; Skin and Connective Tissue Diseases ; 0.444 0.69
Malignant tumor of colon Neoplasms ; Digestive System Diseases ; 0.444 0.69
Colonic Neoplasms Neoplasms ; Digestive System Diseases ; 0.444 0.69
Cytopenia N/A 0.444 0.69
Glioblastoma Neoplasms ; 0.444 0.69
Glomerulonephritis Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.444 0.69
Gonadal Dysgenesis, 46,XY Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Endocrine System Diseases ; 0.444 0.69
Diaphragmatic Hernia Pathological Conditions, Signs and Symptoms ; 0.444 0.69
leukemia Neoplasms ; 0.444 0.69
Leukemia, Myelocytic, Acute Neoplasms ; 0.444 0.69
Myeloid Leukemia, Chronic Neoplasms ; Hemic and Lymphatic Diseases ; 0.444 0.69
Acute Promyelocytic Leukemia Neoplasms ; 0.444 0.69
Lung Neoplasms Neoplasms ; Respiratory Tract Diseases ; 0.444 0.69
Acute Myeloid Leukemia, M1 Neoplasms ; 0.444 0.69
Nephroblastoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.444 0.69
Neurilemmoma Neoplasms ; 0.444 0.69
Osteosarcoma Neoplasms ; 0.444 0.69
Pancreatic Neoplasm Neoplasms ; Digestive System Diseases ; Endocrine System Diseases ; 0.444 0.69
Peritoneal Neoplasms Neoplasms ; Digestive System Diseases ; 0.444 0.69
Disorders of Sex Development Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Endocrine System Diseases ; 0.444 0.69
Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.444 0.69
Gonadotropin-Resistant Ovary Syndrome Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.444 0.69
Congenital anemia N/A 0.444 0.69
WAGR Syndrome Neoplasms ; Nervous System Diseases ; Eye Diseases ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Endocrine System Diseases ; 0.444 0.69
Congenital diaphragmatic hernia Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Pathological Conditions, Signs and Symptoms ; 0.444 0.69
Malignant neoplasm of lung Neoplasms ; Respiratory Tract Diseases ; 0.444 0.69
Congenital hernia of foramen of Morgagni Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Pathological Conditions, Signs and Symptoms ; 0.444 0.69
Congenital hernia of foramen of Bochdalek Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Pathological Conditions, Signs and Symptoms ; 0.444 0.69
Desmoplastic Small Round Cell Tumor Neoplasms ; 0.444 0.69
Giant Cell Glioblastoma Neoplasms ; 0.444 0.69
Malignant mesothelioma Neoplasms ; Respiratory Tract Diseases ; 0.444 0.69
Malignant neoplasm of pancreas Neoplasms ; Digestive System Diseases ; Endocrine System Diseases ; 0.444 0.69
Breast Carcinoma Neoplasms ; Skin and Connective Tissue Diseases ; 0.444 0.69
Schwannomatosis, Plexiform Neoplasms ; 0.444 0.69
Malignant Peripheral Nerve Sheath Tumor Neoplasms ; 0.444 0.69
Denys-Drash Syndrome Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Endocrine System Diseases ; 0.444 0.69
Frasier Syndrome Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Endocrine System Diseases ; 0.444 0.69
Mammary Neoplasms, Human Neoplasms ; Skin and Connective Tissue Diseases ; 0.444 0.69
Mammary Neoplasms Neoplasms ; Skin and Connective Tissue Diseases ; 0.444 0.69
Glioblastoma Multiforme Neoplasms ; 0.444 0.69
Bright Disease Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.444 0.69
MEACHAM SYNDROME (disorder) Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Endocrine System Diseases ; 0.444 0.69
Acute Myeloid Leukemia (AML-M2) Neoplasms ; 0.444 0.69
Bilateral Wilms Tumor Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.444 0.69
Deletion 11p13 Pathological Conditions, Signs and Symptoms ; 0.444 0.69
Swyer Syndrome Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Endocrine System Diseases ; 0.444 0.69
NEPHROTIC SYNDROME, TYPE 4 N/A 0.444 0.69
Hypergonadotropic Ovarian Failure, X-Linked Nervous System Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Endocrine System Diseases ; 0.444 0.69
Intellectual Disability Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ; Mental Disorders ; 0.444 0.69
Peritoneal Surface Malignancy Neoplasms ; Digestive System Diseases ; 0.444 0.69
46,XY partial gonadal dysgenesis N/A 0.444 0.69
NO RESULT FOUND
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