CSF3 (GeneID: 1440) | Homo sapiens
Description: colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438]
Synonyms: C17orf33, GCSF, CSF3OS
Other ID(s): ENSG00000108342, HGNC:2438
Protein Accession Numbers: NP_757373, ENST00000331769, ENST00000583218, ENST00000394149, NP_001171618, ENST00000225474, ENST00000579852, NP_757374, ENST00000394148, NP_000750, ENST00000577675
Statistics: ClinVar(5) gnomAD(182) COSMIC(57)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000225474 ENST00000331769 ENST00000394148 ENST00000394149 You are here now! ENST00000577675 ENST00000579852 ENST00000583218 NP_000750 NP_001171618 NP_757373 You are here now! NP_757374


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
NO DOMAINS EXIST

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Spontaneous abortion Female Urogenital Diseases and Pregnancy Complications ; 0.421 0.828
Abortion, Tubal Female Urogenital Diseases and Pregnancy Complications ; 0.421 0.828
Agranulocytosis Hemic and Lymphatic Diseases ; 0.421 0.828
Anemia Hemic and Lymphatic Diseases ; 0.421 0.828
Aplastic Anemia Hemic and Lymphatic Diseases ; 0.421 0.828
Arthralgia Musculoskeletal Diseases ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Malignant neoplasm of urinary bladder Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.421 0.828
Bladder Neoplasm Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.421 0.828
Malignant neoplasm of breast Neoplasms ; Skin and Connective Tissue Diseases ; 0.421 0.828
Carcinoma Neoplasms ; 0.421 0.828
Malignant neoplasm of skin Neoplasms ; Skin and Connective Tissue Diseases ; 0.421 0.828
Non-Small Cell Lung Carcinoma Neoplasms ; Respiratory Tract Diseases ; 0.421 0.828
Carcinoma, Transitional Cell Neoplasms ; 0.421 0.828
Cardiomyopathy, Dilated Cardiovascular Diseases ; 0.421 0.828
Endogenous depression Mental Disorders ; 0.421 0.828
Depressive disorder Mental Disorders ; 0.421 0.828
Scleroderma Skin and Connective Tissue Diseases ; 0.421 0.828
Diarrhea Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Drug toxicity Chemically-Induced Disorders ; 0.421 0.828
Toxic Epidermal Necrolysis Stomatognathic Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ; Chemically-Induced Disorders ; 0.421 0.828
Esophageal Neoplasms Neoplasms ; Digestive System Diseases ; 0.421 0.828
Fever Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Fibrosis Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Gastrointestinal Diseases Digestive System Diseases ; 0.421 0.828
Head and Neck Neoplasms Neoplasms ; 0.421 0.828
Head Neoplasms Neoplasms ; 0.421 0.828
Headache Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Heart Diseases Cardiovascular Diseases ; 0.421 0.828
Heart failure Cardiovascular Diseases ; 0.421 0.828
Congestive heart failure Cardiovascular Diseases ; 0.421 0.828
Hemangiosarcoma Neoplasms ; 0.421 0.828
Hepatic Veno-Occlusive Disease Digestive System Diseases ; Cardiovascular Diseases ; 0.421 0.828
Hepatitis, Toxic Digestive System Diseases ; Chemically-Induced Disorders ; 0.421 0.828
Hodgkin Disease Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Hyperbilirubinemia Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Hypertrophy Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Infarction Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Kidney Diseases Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.421 0.828
Left-Sided Heart Failure Cardiovascular Diseases ; 0.421 0.828
leiomyosarcoma Neoplasms ; 0.421 0.828
Leukemia, Myelocytic, Acute Neoplasms ; 0.421 0.828
Leukopenia Hemic and Lymphatic Diseases ; 0.421 0.828
Liver Cirrhosis, Experimental Digestive System Diseases ; 0.421 0.828
Liver diseases Digestive System Diseases ; 0.421 0.828
Liver neoplasms Neoplasms ; Digestive System Diseases ; 0.421 0.828
Reticulosarcoma Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Lymphoma, Mixed-Cell Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Lymphoma, Non-Hodgkin Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Lymphoma, Undifferentiated Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Melancholia Mental Disorders ; 0.421 0.828
melanoma Neoplasms ; 0.421 0.828
Multiple Myeloma Neoplasms ; Cardiovascular Diseases ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Myopathy Musculoskeletal Diseases ; Nervous System Diseases ; 0.421 0.828
Acute Myeloid Leukemia, M1 Neoplasms ; 0.421 0.828
Neck Neoplasms Neoplasms ; 0.421 0.828
Neoplasm Metastasis Neoplasms ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
nervous system disorder Nervous System Diseases ; 0.421 0.828
Neutropenia Hemic and Lymphatic Diseases ; 0.421 0.828
Ocular Headache Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Pain Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Pancytopenia Hemic and Lymphatic Diseases ; 0.421 0.828
Peripheral Neuropathy Nervous System Diseases ; 0.421 0.828
Poisoning Chemically-Induced Disorders ; 0.421 0.828
Pulmonary Fibrosis Respiratory Tract Diseases ; 0.421 0.828
Pyemia Bacterial Infections and Mycoses ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Localized scleroderma Skin and Connective Tissue Diseases ; 0.421 0.828
Septicemia Bacterial Infections and Mycoses ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Skin Neoplasms Neoplasms ; Skin and Connective Tissue Diseases ; 0.421 0.828
Soft Tissue Neoplasms Neoplasms ; 0.421 0.828
Staphylococcal Infections Bacterial Infections and Mycoses ; 0.421 0.828
Stevens-Johnson Syndrome Stomatognathic Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ; Chemically-Induced Disorders ; 0.421 0.828
Stomatitis Stomatognathic Diseases ; 0.421 0.828
Thrombocytopenia Hemic and Lymphatic Diseases ; 0.421 0.828
Unipolar Depression Mental Disorders ; 0.421 0.828
Adverse reaction to drug Chemically-Induced Disorders ; 0.421 0.828
Uterine Neoplasms Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; 0.421 0.828
B-Cell Lymphomas Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
High Grade Lymphoma (neoplasm) Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Lymphoma, Intermediate-Grade Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Low Grade Lymphoma (neoplasm) Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Diffuse Mixed-Cell Lymphoma Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Lymphoma, Small Noncleaved-Cell Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Lymphoma, AIDS-Related Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Neoplasms, Second Primary Neoplasms ; 0.421 0.828
Injuries, Acute Brain Nervous System Diseases ; Wounds and Injuries ; 0.421 0.828
Hamman-Rich syndrome Respiratory Tract Diseases ; 0.421 0.828
Depressive Syndrome Mental Disorders ; 0.421 0.828
Liver Dysfunction Digestive System Diseases ; 0.421 0.828
Neoplasms, Therapy-Associated Neoplasms ; 0.421 0.828
Small cell carcinoma of lung Neoplasms ; Respiratory Tract Diseases ; 0.421 0.828
Muscle Weakness Musculoskeletal Diseases ; Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Mixed Cellularity Hodgkin Lymphoma Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Hodgkin lymphoma, lymphocyte depletion Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Uterine Cancer Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; 0.421 0.828
Polyarthralgia Musculoskeletal Diseases ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Liver Failure, Acute Digestive System Diseases ; 0.421 0.828
Hypoplastic anemia Hemic and Lymphatic Diseases ; 0.421 0.828
Anaplastic carcinoma Neoplasms ; 0.421 0.828
Carcinoma, Spindle-Cell Neoplasms ; 0.421 0.828
Undifferentiated carcinoma Neoplasms ; 0.421 0.828
Carcinomatosis Neoplasms ; 0.421 0.828
Leiomyosarcoma, Epithelioid Neoplasms ; 0.421 0.828
Leiomyosarcoma, Myxoid Neoplasms ; 0.421 0.828
Adult Hodgkin Lymphoma Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Pain, Burning Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Ache Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Radiating pain Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Heart Failure, Right-Sided Cardiovascular Diseases ; 0.421 0.828
Ventricular Dysfunction, Left Cardiovascular Diseases ; 0.421 0.828
Sepsis Bacterial Infections and Mycoses ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Linear Scleroderma Skin and Connective Tissue Diseases ; 0.421 0.828
Brain Injuries Nervous System Diseases ; Wounds and Injuries ; 0.421 0.828
Brain Lacerations Nervous System Diseases ; Wounds and Injuries ; 0.421 0.828
Malignant Head and Neck Neoplasm Neoplasms ; 0.421 0.828
Depression, Neurotic Mental Disorders ; 0.421 0.828
Bone Marrow Neoplasms Neoplasms ; Hemic and Lymphatic Diseases ; 0.421 0.828
Inflammatory disease of mucous membrane Digestive System Diseases ; Stomatognathic Diseases ; 0.421 0.828
Malignant neoplasm of liver Neoplasms ; Digestive System Diseases ; 0.421 0.828
Throbbing Headache Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Bilateral Headache Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Brain Injuries, Focal Nervous System Diseases ; Wounds and Injuries ; 0.421 0.828
Pain, Splitting Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Pain, Crushing Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Generalized Headache Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Malignant neoplasm of esophagus Neoplasms ; Digestive System Diseases ; 0.421 0.828
Functional Gastrointestinal Disorders Digestive System Diseases ; 0.421 0.828
Breast Carcinoma Neoplasms ; Skin and Connective Tissue Diseases ; 0.421 0.828
Cancer of Neck Neoplasms ; 0.421 0.828
Cancer of Head Neoplasms ; 0.421 0.828
Orthostatic Headache Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Periorbital Headache Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Retro-Ocular Headache Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Sharp Headache Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Vertex Headache Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Pain, Migratory Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Suffering, Physical Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Impairment, Light Touch Sensation Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Pain Sensation Diminished Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Pinprick Sensation Diminished Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Position Sense Disorders Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Proprioceptive Disorders Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Thermal Sensation Disorders Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Somatosensory Disorders Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Drug-Induced Liver Disease Digestive System Diseases ; Chemically-Induced Disorders ; 0.421 0.828
Treatment related secondary malignancy Neoplasms ; 0.421 0.828
Hemicrania Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Upper Aerodigestive Tract Neoplasms Neoplasms ; 0.421 0.828
Mammary Neoplasms, Human Neoplasms ; Skin and Connective Tissue Diseases ; 0.421 0.828
Hepatitis, Drug-Induced Digestive System Diseases ; Chemically-Induced Disorders ; 0.421 0.828
Lymphocyte Rich Classical Hodgkin Lymphoma Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Drug-Induced Stevens Johnson Syndrome Stomatognathic Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ; Chemically-Induced Disorders ; 0.421 0.828
Staphylococcus aureus infection Bacterial Infections and Mycoses ; 0.421 0.828
Nodular Lymphocyte Predominant Hodgkin Lymphoma Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases ; 0.421 0.828
Mammary Neoplasms Neoplasms ; Skin and Connective Tissue Diseases ; 0.421 0.828
Morphea Skin and Connective Tissue Diseases ; 0.421 0.828
Cholera Infantum Digestive System Diseases ; 0.421 0.828
Oral Mucositis Stomatognathic Diseases ; 0.421 0.828
Cirrhosis Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Severe Sepsis Bacterial Infections and Mycoses ; Pathological Conditions, Signs and Symptoms ; 0.421 0.828
Acute Myeloid Leukemia (AML-M2) Neoplasms ; 0.421 0.828
Myocardial Failure Cardiovascular Diseases ; 0.421 0.828
Heart Decompensation Cardiovascular Diseases ; 0.421 0.828
Drug-Induced Acute Liver Injury Digestive System Diseases ; Chemically-Induced Disorders ; 0.421 0.828
Mycoplasma-Induced Stevens-Johnson Syndrome Stomatognathic Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ; Chemically-Induced Disorders ; 0.421 0.828
Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum Stomatognathic Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ; Chemically-Induced Disorders ; 0.421 0.828
Lymphoma, Diffuse Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.421 0.828
Chemical and Drug Induced Liver Injury Digestive System Diseases ; Chemically-Induced Disorders ; 0.421 0.828
Chemically-Induced Liver Toxicity Digestive System Diseases ; Chemically-Induced Disorders ; 0.421 0.828
NO RESULT FOUND
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