Runx3 (GeneID: 12399) | Mus musculus
Description: runt related transcription factor 3 [Source:MGI Symbol;Acc:MGI:102672]
Synonyms: AML2, Pebp2a3, Cbfa3
Other ID(s): ENSMUSG00000070691, MGI:102672
Protein Accession Numbers: NP_062706, NP_001355979, XP_006538569
Statistics: ClinVar(2) gnomAD(382) COSMIC(179) PTM(34)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000308873 You are here now! ENST00000338888 ENST00000399916 ENST00000540420 NP_001026850 NP_001307601 NP_004341 You are here now!


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF00853 Runt Runt domain 55-183 CL0073 P53-like Homo sapiens
PF08504 RunxI Runx inhibition domain 316-415 Homo sapiens

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Adenocarcinoma Neoplasms ; 0.494 0.69
Celiac Disease Digestive System Diseases ; Nutritional and Metabolic Diseases ; 0.494 0.69
Esophageal Neoplasms Neoplasms ; Digestive System Diseases ; 0.494 0.69
Glioblastoma Neoplasms ; 0.494 0.69
Leukemia, Myelocytic, Acute Neoplasms ; 0.494 0.69
Lung Neoplasms Neoplasms ; Respiratory Tract Diseases ; 0.494 0.69
Malignant neoplasm of stomach Neoplasms ; Digestive System Diseases ; 0.494 0.69
Acute Myeloid Leukemia, M1 Neoplasms ; 0.494 0.69
Pustulosis of Palms and Soles Skin and Connective Tissue Diseases ; 0.494 0.69
Polycystic Ovary Syndrome Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.494 0.69
Psoriasis Skin and Connective Tissue Diseases ; 0.494 0.69
Ankylosing spondylitis Musculoskeletal Diseases ; 0.494 0.69
Stomach Neoplasms Neoplasms ; Digestive System Diseases ; 0.494 0.69
Adenocarcinoma, Basal Cell Neoplasms ; 0.494 0.69
Adenocarcinoma, Oxyphilic Neoplasms ; 0.494 0.69
Carcinoma, Cribriform Neoplasms ; 0.494 0.69
Carcinoma, Granular Cell Neoplasms ; 0.494 0.69
Adenocarcinoma, Tubular Neoplasms ; 0.494 0.69
Malignant neoplasm of lung Neoplasms ; Respiratory Tract Diseases ; 0.494 0.69
Giant Cell Glioblastoma Neoplasms ; 0.494 0.69
Malignant neoplasm of esophagus Neoplasms ; Digestive System Diseases ; 0.494 0.69
Sclerocystic Ovaries Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.494 0.69
Glioblastoma Multiforme Neoplasms ; 0.494 0.69
Hereditary Diffuse Gastric Cancer Neoplasms ; Digestive System Diseases ; 0.494 0.69
Acute Myeloid Leukemia (AML-M2) Neoplasms ; 0.494 0.69
Liver carcinoma Neoplasms ; Digestive System Diseases ; 0.494 0.69
NO RESULT FOUND
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