CLU (GeneID: 677866) | Macaca mulatta
Description: clusterin [Source:NCBI gene;Acc:677866]
Synonyms:
Other ID(s): ENSMMUG00000021516
Protein Accession Numbers: XP_015000485, NP_001182403
Statistics: ClinVar(14) gnomAD(1203) COSMIC(432) PTM(26)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000316403 You are here now! ENST00000405140 You are here now! ENST00000519472 ENST00000519742 ENST00000520491 ENST00000520796 ENST00000521770 ENST00000522098 ENST00000522238 ENST00000522413 ENST00000523396 ENST00000523500 You are here now! ENST00000523589 ENST00000546343 ENST00000560366 ENST00000560566 NP_001822 You are here now!


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF01093 Clusterin Clusterin 30-446 Homo sapiens

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Alzheimer's Disease Nervous System Diseases ; Mental Disorders ; 0.456 0.793
Presenile dementia Nervous System Diseases ; Mental Disorders ; 0.456 0.793
Drug toxicity Chemically-Induced Disorders ; 0.456 0.793
Hepatitis, Toxic Digestive System Diseases ; Chemically-Induced Disorders ; 0.456 0.793
Jacksonian Seizure Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Kidney Diseases Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.456 0.793
Kidney Failure, Acute Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.456 0.793
Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases ; Immune System Diseases ; 0.456 0.793
melanoma Neoplasms ; 0.456 0.793
Pathologic Neovascularization Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Degenerative polyarthritis Musculoskeletal Diseases ; 0.456 0.793
Prostatic Neoplasms Neoplasms ; Male Urogenital Diseases ; 0.456 0.793
Schizophrenia Mental Disorders ; 0.456 0.793
Seizures Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Adverse reaction to drug Chemically-Induced Disorders ; 0.456 0.793
Osteoarthrosis Deformans Musculoskeletal Diseases ; 0.456 0.793
Juvenile-Onset Still Disease Musculoskeletal Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ; 0.456 0.793
Complex partial seizures Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Generalized seizures Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Seizures, Clonic Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Libman-Sacks Disease Skin and Connective Tissue Diseases ; Immune System Diseases ; 0.456 0.793
Visual seizure Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Tonic Seizures Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Epileptic drop attack Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Familial Alzheimer Disease (FAD) Nervous System Diseases ; Mental Disorders ; 0.456 0.793
Atrophic Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Malignant neoplasm of prostate Neoplasms ; Male Urogenital Diseases ; 0.456 0.793
Seizures, Somatosensory Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Seizures, Auditory Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Olfactory seizure Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Gustatory seizure Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Vertiginous seizure Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Alzheimer Disease, Late Onset Nervous System Diseases ; Mental Disorders ; 0.456 0.793
Tonic - clonic seizures Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Acute Confusional Senile Dementia Nervous System Diseases ; Mental Disorders ; 0.456 0.793
Alzheimer's Disease, Focal Onset Nervous System Diseases ; Mental Disorders ; 0.456 0.793
Alzheimer Disease, Early Onset Nervous System Diseases ; Mental Disorders ; 0.456 0.793
Non-epileptic convulsion Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Single Seizure Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Atonic Absence Seizures Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Convulsive Seizures Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Seizures, Focal Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Seizures, Sensory Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Drug-Induced Liver Disease Digestive System Diseases ; Chemically-Induced Disorders ; 0.456 0.793
Hepatitis, Drug-Induced Digestive System Diseases ; Chemically-Induced Disorders ; 0.456 0.793
Acute Kidney Insufficiency Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.456 0.793
AMYOTROPHIC LATERAL SCLEROSIS 1 Nervous System Diseases ; Nutritional and Metabolic Diseases ; 0.456 0.793
Amyotrophic Lateral Sclerosis, Sporadic Nervous System Diseases ; Nutritional and Metabolic Diseases ; 0.456 0.793
Acute kidney injury Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.456 0.793
Juvenile arthritis Musculoskeletal Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ; 0.456 0.793
Nonepileptic Seizures Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Drug-Induced Acute Liver Injury Digestive System Diseases ; Chemically-Induced Disorders ; 0.456 0.793
Juvenile psoriatic arthritis Musculoskeletal Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ; 0.456 0.793
Convulsions Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Chemical and Drug Induced Liver Injury Digestive System Diseases ; Chemically-Induced Disorders ; 0.456 0.793
Chemically-Induced Liver Toxicity Digestive System Diseases ; Chemically-Induced Disorders ; 0.456 0.793
Absence Seizures Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Epileptic Seizures Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Myoclonic Seizures Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
Generalized Absence Seizures Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.456 0.793
NO RESULT FOUND
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