Tnfsf10 (GeneID: 246775) | Rattus norvegicus
Description: TNF superfamily member 10 [Source:RGD Symbol;Acc:628734]
Synonyms: Tnlg6a, Trail
Other ID(s): ENSRNOG00000013269
Protein Accession Numbers: XP_017446123, NP_663714, XP_017446122, XP_017446121
Statistics: ClinVar(3) gnomAD(104) COSMIC(130) PTM(6)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000241261 ENST00000420541 You are here now! ENST00000430881 NP_001177871 You are here now! NP_001177872 NP_003801


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF00229 TNF TNF(Tumour Necrosis Factor) family 152-280 CL0100 C1q_TNF Homo sapiens

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Spontaneous abortion Female Urogenital Diseases and Pregnancy Complications ; 0.44 0.828
Abortion, Tubal Female Urogenital Diseases and Pregnancy Complications ; 0.44 0.828
Malignant neoplasm of breast Neoplasms ; Skin and Connective Tissue Diseases ; 0.44 0.828
Malignant tumor of colon Neoplasms ; Digestive System Diseases ; 0.44 0.828
Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.44 0.828
Colonic Neoplasms Neoplasms ; Digestive System Diseases ; 0.44 0.828
Colorectal Carcinoma Neoplasms ; Digestive System Diseases ; 0.44 0.828
Colorectal Neoplasms Neoplasms ; Digestive System Diseases ; 0.44 0.828
Endometrial Neoplasms Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; 0.44 0.828
Glioblastoma Neoplasms ; 0.44 0.828
Glioma Neoplasms ; 0.44 0.828
Influenza Virus Diseases ; Respiratory Tract Diseases ; 0.44 0.828
Kidney Neoplasm Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.44 0.828
leukemia Neoplasms ; 0.44 0.828
Leukemia, Myelocytic, Acute Neoplasms ; 0.44 0.828
Liver neoplasms Neoplasms ; Digestive System Diseases ; 0.44 0.828
Mammary Neoplasms, Experimental Neoplasms ; 0.44 0.828
Acute Myeloid Leukemia, M1 Neoplasms ; 0.44 0.828
Neoplasm Metastasis Neoplasms ; Pathological Conditions, Signs and Symptoms ; 0.44 0.828
Neoplasms, Experimental Neoplasms ; 0.44 0.828
Pathologic Neovascularization Pathological Conditions, Signs and Symptoms ; 0.44 0.828
Neuroblastoma Neoplasms ; 0.44 0.828
Pancreatic Neoplasm Neoplasms ; Digestive System Diseases ; Endocrine System Diseases ; 0.44 0.828
Prostatic Neoplasms Neoplasms ; Male Urogenital Diseases ; 0.44 0.828
Injuries, Acute Brain Nervous System Diseases ; Wounds and Injuries ; 0.44 0.828
Adenocarcinoma of lung (disorder) Neoplasms ; Respiratory Tract Diseases ; 0.44 0.828
mixed gliomas Neoplasms ; 0.44 0.828
Brain Injuries Nervous System Diseases ; Wounds and Injuries ; 0.44 0.828
Brain Lacerations Nervous System Diseases ; Wounds and Injuries ; 0.44 0.828
Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.44 0.828
Giant Cell Glioblastoma Neoplasms ; 0.44 0.828
Malignant neoplasm of liver Neoplasms ; Digestive System Diseases ; 0.44 0.828
Malignant neoplasm of pancreas Neoplasms ; Digestive System Diseases ; Endocrine System Diseases ; 0.44 0.828
Malignant neoplasm of prostate Neoplasms ; Male Urogenital Diseases ; 0.44 0.828
Brain Injuries, Focal Nervous System Diseases ; Wounds and Injuries ; 0.44 0.828
Endometrial Carcinoma Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; 0.44 0.828
Malignant Glioma Neoplasms ; 0.44 0.828
Breast Carcinoma Neoplasms ; Skin and Connective Tissue Diseases ; 0.44 0.828
Malignant neoplasm of kidney Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.44 0.828
ovarian neoplasm Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.44 0.828
Malignant neoplasm of ovary Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.44 0.828
Mammary Neoplasms, Human Neoplasms ; Skin and Connective Tissue Diseases ; 0.44 0.828
Chromophobe Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.44 0.828
Sarcomatoid Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.44 0.828
Collecting Duct Carcinoma of the Kidney Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.44 0.828
Papillary Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.44 0.828
Mammary Neoplasms Neoplasms ; Skin and Connective Tissue Diseases ; 0.44 0.828
Colorectal Cancer Neoplasms ; Digestive System Diseases ; 0.44 0.828
Glioblastoma Multiforme Neoplasms ; 0.44 0.828
Acute Myeloid Leukemia (AML-M2) Neoplasms ; 0.44 0.828
Liver carcinoma Neoplasms ; Digestive System Diseases ; 0.44 0.828
NO RESULT FOUND
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