ConVarT

Amino Acid Conservation Percentage (Human versus Organisms with ClinVar and gnomAD Data)

Total amino acid identity (%)

Variation associated amino acid identity (%)

ClinVar Data

Show entries

Variation ID	Allele ID	RS Number	Variant Type	Record	Alteration	Clinicial Sig.	Last Update	Phenotypes	Cytogenetic
16499	31538	rs121913076	single nucleotide variant	NM_000043.6(FAS):c.721A>C (p.Thr241Pro)	p.Thr220Pro	Pathogenic	Autoimmune lymphoproliferative syndrome, type 1a	no assertion criteria provided	RCV000017963
16501	31540	rs121913077	single nucleotide variant	NM_000043.6(FAS):c.817C>T (p.Gln273Ter)	p.Gln252Ter	Pathogenic	Autoimmune lymphoproliferative syndrome, type 1a\|Autoimmune lymphoproliferative syndrome	criteria provided, single submitter	RCV000017965\|RCV001071386
16502	31541	rs121913078	single nucleotide variant	NM_000043.6(FAS):c.361C>T (p.Arg121Trp)	p.Arg121Trp	Pathogenic	Autoimmune lymphoproliferative syndrome, type 1a	no assertion criteria provided	RCV000017966
16503	31542	rs121913079	single nucleotide variant	NM_000043.6(FAS):c.695A>G (p.Tyr232Cys)	p.Tyr211Cys	Uncertain significance	Autoimmune lymphoproliferative syndrome, type 1a\|Autoimmune lymphoproliferative syndrome	criteria provided, single submitter	RCV000017967\|RCV000814654
16504	31543	rs28929498	single nucleotide variant	NM_000043.6(FAS):c.779A>T (p.Asp260Val)	p.Asp239Val	Pathogenic	Autoimmune lymphoproliferative syndrome, type 1a	no assertion criteria provided	RCV000017968
16505	31544	rs121913080	single nucleotide variant	NM_000043.6(FAS):c.749G>C (p.Arg250Pro)	p.Arg229Pro	Likely pathogenic	Autoimmune lymphoproliferative syndrome, type 1a\|Autoimmune lymphoproliferative syndrome\|not provided	criteria provided, single submitter	RCV000017969\|RCV000638906\|RCV001701481
16506	31545	rs121913081	single nucleotide variant	NM_000043.6(FAS):c.809C>T (p.Thr270Ile)	p.Thr249Ile	Pathogenic	Autoimmune lymphoproliferative syndrome, type 1a	no assertion criteria provided	RCV000017970
16508	31547	rs606231364	single nucleotide variant	NM_000043.6(FAS):c.73G>A (p.Ala25Thr)	p.Ala25Thr	Pathogenic	Autoimmune lymphoproliferative syndrome, type 1a	no assertion criteria provided	RCV000017972
16510	31549	rs121913082	single nucleotide variant	NM_000043.6(FAS):c.763A>G (p.Asn255Asp)	p.Asn234Asp	Pathogenic	SQUAMOUS CELL CARCINOMA, BURN SCAR-RELATED, SOMATIC	no assertion criteria provided	RCV000017974
16511	31550	rs121913083	single nucleotide variant	NM_000043.6(FAS):c.353A>G (p.Asn118Ser)	p.Asn118Ser	Pathogenic	SQUAMOUS CELL CARCINOMA, BURN SCAR-RELATED, SOMATIC	no assertion criteria provided	RCV000017975
16513	31552	rs121913085	single nucleotide variant	NM_000043.6(FAS):c.740G>C (p.Gly247Ala)	p.Gly226Ala	Pathogenic	Autoimmune lymphoproliferative syndrome, type 1a	no assertion criteria provided	RCV000017977
16516	31555	rs121913086	single nucleotide variant	NM_000043.6(FAS):c.778G>T (p.Asp260Tyr)	p.Asp239Tyr	Pathogenic	Autoimmune lymphoproliferative syndrome, type 1a	no assertion criteria provided	RCV000017980
100802	106662	rs483352683	single nucleotide variant	NM_000043.6(FAS):c.785T>C (p.Ile262Thr)	p.Ile241Thr	Uncertain significance	not provided	no assertion criteria provided	RCV000087160
134371	138110	rs3218619	single nucleotide variant	NM_000043.6(FAS):c.46G>A (p.Ala16Thr)	p.Ala16Thr	Benign/Likely benign	not specified\|Autoimmune lymphoproliferative syndrome\|not provided	criteria provided, multiple submitters, no conflicts	RCV000121045\|RCV000259335\|RCV001640107
134372	138111	rs3218614	single nucleotide variant	NM_000043.6(FAS):c.365C>T (p.Thr122Ile)	p.Thr122Ile	Benign/Likely benign	not specified\|Autoimmune lymphoproliferative syndrome\|not provided	criteria provided, multiple submitters, no conflicts	RCV000121046\|RCV000290355\|RCV001705893
134373	138112	rs574338716	single nucleotide variant	NM_000043.6(FAS):c.432C>A (p.Asp144Glu)	p.Asp144Glu	Uncertain significance	not specified\|Autoimmune lymphoproliferative syndrome	criteria provided, single submitter	RCV000121047\|RCV000804916
134374	138113	rs56006128	single nucleotide variant	NM_000043.6(FAS):c.580G>A (p.Glu194Lys)	p.Glu173Lys	Conflicting interpretations of pathogenicity	not specified\|Autoimmune lymphoproliferative syndrome\|not provided	criteria provided, conflicting interpretations	RCV000121048\|RCV000407819\|RCV000766928
134375	138114	rs587778348	single nucleotide variant	NM_000043.6(FAS):c.756T>G (p.Asn252Lys)	p.Asn231Lys	not provided	not specified	no assertion provided	RCV000121049
155871	165620	rs3218613	single nucleotide variant	NM_000043.6(FAS):c.183G>A (p.Lys61=)	p.Lys61=	Benign	Autoimmune lymphoproliferative syndrome\|not provided	criteria provided, multiple submitters, no conflicts	RCV000143988\|RCV001705940
210992	207798	rs28362318	single nucleotide variant	NM_000043.6(FAS):c.369G>A (p.Gln123=)	p.Gln123=	Benign/Likely benign	not specified\|Autoimmune lymphoproliferative syndrome\|not provided	criteria provided, multiple submitters, no conflicts	RCV000194021\|RCV000328893\|RCV000829368

Showing 1 to 20 of 91 entries

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gnomAD

Frameshift Variant

Inframe Insertion

Missense Variant

Splice Region Variant

Stop Gained

Stop Lost

Synonymous Variant

Show entries

Variant ID	Transcript ID	Alteration	Annotation	Allele C.	Allele N.	Allele F.	rsNumber	Flags
10-90750640-G-C	ENST00000357339	p.Gly3Arg	Missense Variant	0	0	0	rs759288204
10-90750645-C-G	ENST00000357339	p.Ile4Met	Missense Variant	0	0	0	rs771825085
10-90750648-G-A	ENST00000357339	p.Trp5Ter	Stop Gained	1	31378	0.000032	rs1290926270	lof_flag
10-90750652-C-T	ENST00000357339	p.Leu7Phe	Missense Variant	0	0	0	rs775316075
10-90750654-C-T	ENST00000357339	p.Leu7Leu	Synonymous Variant	0	0	0	rs1312703118
10-90750657-A-G	ENST00000357339	p.Leu8Leu	Synonymous Variant	0	0	0	rs760596246
10-90762787-T-C	ENST00000357339	p.Val11Ala	Missense Variant	0	0	0	rs761692893
10-90762788-T-A	ENST00000357339	p.Val11Val	Splice Region Variant	42	31402	0.001337	rs113022949
10-90762789-C-T	ENST00000357339	p.Leu12Phe	Missense Variant	0	0	0	rs772912891
10-90762793-C-A	ENST00000357339	p.Thr13Lys	Missense Variant	0	0	0	rs372880667
10-90762793-C-T	ENST00000357339	p.Thr13Met	Missense Variant	5	31402	0.000159	rs372880667
10-90762794-G-T	ENST00000357339	p.Thr13Thr	Synonymous Variant	1	31400	0.000032	rs377196867
10-90762801-G-A	ENST00000357339	p.Ala16Thr	Missense Variant	1117	31392	0.035582	rs3218619
10-90762806-A-C	ENST00000357339	p.Arg17Ser	Missense Variant	0	0	0	rs756522969
10-90762807-T-G	ENST00000357339	p.Leu18Val	Missense Variant	0	0	0	rs764468017
10-90762810-T-C	ENST00000357339	p.Ser19Pro	Missense Variant	0	0	0	rs1199807438
10-90762811-C-T	ENST00000357339	p.Ser19Leu	Missense Variant	0	0	0	rs754339875
10-90762812-G-A	ENST00000357339	p.Ser19Ser	Synonymous Variant	0	0	0	rs757754872
10-90762816-A-G	ENST00000357339	p.Lys21Glu	Missense Variant	0	0	0	rs1174183388
10-90762821-T-C	ENST00000357339	p.Ser22Ser	Synonymous Variant	1	31402	0.000032	rs1381204725

Showing 1 to 20 of 206 entries

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Post-translational Modifications (PTMs)

O-GalNAc

Phosphorylation

Ubiquitination

Show entries

Gene Name	ACC ID	PTM Type	Position	Mod-rsd	Site +/-7 Aa	Mw_kd	Site grpID
FAS	P25445	Ubiquitination	204	K204-ub	KTCRKHRkENQGsHE	37.73	964514812
FAS	P25445	Phosphorylation	209	S209-p	HRkENQGsHEsPtLN	37.73	3189340
FAS	P25445	Phosphorylation	212	S212-p	ENQGsHEsPtLNPEt	37.73	3189343
FAS	P25445	Phosphorylation	214	T214-p	QGsHEsPtLNPEtVA	37.73	3189346
FAS	P25445	Phosphorylation	219	T219-p	sPtLNPEtVAINLsD	37.73	3189349
FAS	P25445	Phosphorylation	225	S225-p	EtVAINLsDVDLsKy	37.73	4704870
FAS	P25445	Phosphorylation	230	S230-p	NLsDVDLsKyItTIA	37.73	4704879
FAS	P25445	Phosphorylation	232	Y232-p	sDVDLsKyItTIAGV	37.73	455221
FAS	P25445	Phosphorylation	234	T234-p	VDLsKyItTIAGVMt	37.73	23105809
FAS	P25445	Phosphorylation	241	T241-p	tTIAGVMtLsQVKGF	37.73	23105812
FAS	P25445	Phosphorylation	243	S243-p	IAGVMtLsQVKGFVR	37.73	15403420
FAS	P25445	Ubiquitination	263	K263-ub	EAKIDEIkNDNVQDT	37.73	21174632
FAS	P25445	Ubiquitination	274	K274-ub	VQDTAEQkVQLLRNW	37.73	964514814
FAS	P25445	Ubiquitination	287	K287-ub	NWHQLHGkkEAyDtL	37.73	964514816
FAS	P25445	Ubiquitination	288	K288-ub	WHQLHGkkEAyDtLI	37.73	21174634
FAS	P25445	Phosphorylation	291	Y291-p	LHGkkEAyDtLIkDL	37.73	455222
FAS	P25445	Phosphorylation	293	T293-p	GkkEAyDtLIkDLKk	37.73	27448977
FAS	P25445	Ubiquitination	296	K296-ub	EAyDtLIkDLKkANL	37.73	964514818
FAS	P25445	Ubiquitination	300	K300-ub	tLIkDLKkANLCtLA	37.73	964514820
FAS	P25445	Phosphorylation	305	T305-p	LKkANLCtLAEkIQt	37.73	27448975

Showing 1 to 20 of 33 entries

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Catalogue of Somatic Mutations in Cancer (COSMIC)

Deletion - Frameshift

Insertion - Frameshift

Substitution - Coding Silent

Substitution - Missense

Substitution - Nonsense

Unknown

Show entries

Gene Name	Transcript ID	Sample name	Primary Site	Primary Histology	Mutation ID	Mutation CDS	Mutation Aa	Mutation Desc.	FATHMM Prediction	FATHMM Score	Mutation Somatic Status	PUBMED PMID	Tumor Origin	Position
FAS_ENST00000357339	ENST00000357339	8057490	pancreas	carcinoma	32333387	c.30+555C>T	p.?	Unknown	NEUTRAL	.01084	Confirmed somatic variant	PMID: N/A	NS	0
FAS_ENST00000357339	ENST00000357339	SJHGG028_D	central_nervous_system	glioma	32334048	c.589-545G>A	p.?	Unknown	NEUTRAL	.03114	Confirmed somatic variant	PMID: 24705251	NS	0
FAS_ENST00000357339	ENST00000357339	CPCG0336-F1	prostate	carcinoma	32333842	c.31-2449dup	p.?	Unknown			Confirmed somatic variant	PMID: N/A	primary	0
FAS_ENST00000357339	ENST00000357339	LP6007414-DNA_A02	oesophagus	carcinoma	32332478	c.197-453T>G	p.?	Unknown	NEUTRAL	.03968	Confirmed somatic variant	PMID: N/A	primary	0
FAS_ENST00000357339	ENST00000357339	PD6722a	breast	carcinoma	32333428	c.614-1G>C	p.?	Unknown	PATHOGENIC	.9323	Confirmed somatic variant	PMID: N/A	primary	0
FAS_ENST00000357339	ENST00000357339	HCC20T	liver	carcinoma	32332076	c.594A>G	p.T198=	Substitution - coding silent	NEUTRAL	.00352	Reported in another cancer sample as somatic	PMID: N/A	primary	198
FAS_ENST00000357339	ENST00000357339	TCGA-D1-A16J-01	endometrium	carcinoma	32332437	c.504del	p.V169*	Deletion - Frameshift			Variant of unknown origin	PMID: N/A	primary	169
FAS_ENST00000357339	ENST00000357339	60T	liver	other	32333392	c.196+2247A>T	p.?	Unknown	NEUTRAL	.07844	Confirmed somatic variant	PMID: N/A	primary	0
FAS_ENST00000357339	ENST00000357339	TNKTL24	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	32333857	c.197-1730C>A	p.?	Unknown	NEUTRAL	.02505	Confirmed somatic variant	PMID: N/A	primary	0
FAS_ENST00000357339	ENST00000357339	TCGA-EE-A3JB-06	skin	malignant_melanoma	32334063	c.334G>A	p.G112S	Substitution - Missense	PATHOGENIC	.91263	Confirmed somatic variant	PMID: N/A	NS	112
FAS_ENST00000357339	ENST00000357339	CHG-91T	liver	other	32333641	c.686G>T	p.R229L	Substitution - Missense	PATHOGENIC	.91514	Confirmed somatic variant	PMID: N/A	primary	229
FAS_ENST00000357339	ENST00000357339	1092573	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	32331981	c.838_839insA	p.A280Dfs*20	Insertion - Frameshift			Reported in another cancer sample as somatic	PMID: 11245438	NS	20
FAS_ENST00000357339	ENST00000357339	P94	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	32332102	c.613+1G>A	p.?	Unknown	PATHOGENIC	.87229	Reported in another cancer sample as somatic	PMID: 32187361	primary	0
FAS_ENST00000357339	ENST00000357339	THCC_130T	liver	other	32334327	c.505+286T>C	p.?	Unknown	NEUTRAL	.08371	Confirmed somatic variant	PMID: N/A	primary	0
FAS_ENST00000357339	ENST00000357339	TCGA-CR-7402-01	upper_aerodigestive_tract	carcinoma	32332120	c.138T>A	p.T46=	Substitution - coding silent	NEUTRAL	.0138	Confirmed somatic variant	PMID: N/A	NS	46
FAS_ENST00000357339	ENST00000357339	2760231	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	32331918	c.613+2T>C	p.?	Unknown	PATHOGENIC	.83145	Reported in another cancer sample as somatic	PMID: 29481902	primary	0
FAS_ENST00000357339	ENST00000357339	1092577	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	32331981	c.838_839insA	p.A280Dfs*20	Insertion - Frameshift			Reported in another cancer sample as somatic	PMID: 11245438	NS	20
FAS_ENST00000357339	ENST00000357339	2760225	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	32333589	c.589-1G>C	p.?	Unknown	PATHOGENIC	.84962	Variant of unknown origin	PMID: 29481902	primary	0
FAS_ENST00000357339	ENST00000357339	PCSI_0099_Pa_P	pancreas	carcinoma	32332956	c.31-5658A>T	p.?	Unknown	NEUTRAL	.03524	Confirmed somatic variant	PMID: N/A	primary	0
FAS_ENST00000357339	ENST00000357339	PEN-075	skin	benign_melanocytic_nevus	32332751	c.876C>T	p.I292=	Substitution - coding silent	NEUTRAL	.0107	Variant of unknown origin	PMID: 27890785	NS	292

Showing 1 to 20 of 209 entries

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dbSNP

Gene ID	Transcript ID	Consequence	Position	HGVSp	Impact

Protein Domains (PFAM)

Pfam Domain	Domain Name	Description	Positions	Clan	Clan Name	Organism
NO RESULT FOUND
PF00020	TNFR_c6	TNFR/NGFR cysteine-rich region	85-127	CL0607	TNF_receptor	Homo sapiens
PF00020	TNFR_c6	TNFR/NGFR cysteine-rich region	129-165	CL0607	TNF_receptor	Homo sapiens
PF00531	Death	Death domain	230-314	CL0041	Death	Homo sapiens

List of the diseases from DisGeNET

Disease Name	Disease Category	DSI*	DPI**
Alloxan Diabetes	Nutritional and Metabolic Diseases ; Endocrine System Diseases ;	0.393	0.862
Anemia, Splenic	Hemic and Lymphatic Diseases ;	0.393	0.862
Autoimmune Diseases	Immune System Diseases ;	0.393	0.862
Behcet Syndrome	Stomatognathic Diseases ; Eye Diseases ; Cardiovascular Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Skin and Connective Tissue Diseases ;	0.393	0.862
Malignant neoplasm of urinary bladder	Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ;	0.393	0.862
Bladder Neoplasm	Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ;	0.393	0.862
Squamous cell carcinoma	Neoplasms ;	0.393	0.862
Cardiomyopathy, Dilated	Cardiovascular Diseases ;	0.393	0.862
Diabetes Mellitus, Experimental	Nutritional and Metabolic Diseases ; Endocrine System Diseases ;	0.393	0.862
Diabetes Mellitus, Non-Insulin-Dependent	Nutritional and Metabolic Diseases ; Endocrine System Diseases ;	0.393	0.862
Hematological Disease	Hemic and Lymphatic Diseases ;	0.393	0.862
Hypersplenism	Hemic and Lymphatic Diseases ;	0.393	0.862
Leukemia, Myelocytic, Acute	Neoplasms ;	0.393	0.862
Lung Neoplasms	Neoplasms ; Respiratory Tract Diseases ;	0.393	0.862
Lymphoma, Non-Hodgkin	Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.393	0.862
Malaria, Falciparum	Parasitic Diseases ;	0.393	0.862
Myasthenia Gravis	Nervous System Diseases ; Immune System Diseases ;	0.393	0.862
Acute Myeloid Leukemia, M1	Neoplasms ;	0.393	0.862
Necrosis	Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Nephritis	Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ;	0.393	0.862
Pregnancy Complications, Cardiovascular	Female Urogenital Diseases and Pregnancy Complications ; Cardiovascular Diseases ;	0.393	0.862
Cardiomyopathies, Primary	Cardiovascular Diseases ;	0.393	0.862
Proteinuria	Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Schizophrenia	Mental Disorders ;	0.393	0.862
Myocardial Diseases, Secondary	Cardiovascular Diseases ;	0.393	0.862
Streptozotocin Diabetes	Nutritional and Metabolic Diseases ; Endocrine System Diseases ;	0.393	0.862
Taste Disorders	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Uveomeningoencephalitic Syndrome	Nervous System Diseases ; Eye Diseases ; Immune System Diseases ;	0.393	0.862
Diffuse Large B-Cell Lymphoma	Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.393	0.862
Lymphoma, T-Cell, Cutaneous	Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.393	0.862
Liver Failure, Acute	Digestive System Diseases ;	0.393	0.862
Taste Disorder, Primary	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Taste Disorder, Primary, Sweet	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Taste Disorder, Primary, Salt	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Taste Disorder, Primary, Bitter	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Taste Disorder, Anterior Tongue	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Taste Disorder, Secondary	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Taste Disorder, Secondary, Sweet	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Taste Disorder, Secondary, Salt	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Taste Disorder, Secondary, Bitter	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Taste Disorder, Posterior Tongue	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Taste, Metallic	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ;	0.393	0.862
Malignant neoplasm of lung	Neoplasms ; Respiratory Tract Diseases ;	0.393	0.862
Acute Lung Injury	Respiratory Tract Diseases ;	0.393	0.862
Ventricular Dysfunction, Left	Cardiovascular Diseases ;	0.393	0.862
Granulomatous Slack Skin	Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.393	0.862
Hematologic Neoplasms	Neoplasms ; Hemic and Lymphatic Diseases ;	0.393	0.862
Non-alcoholic Fatty Liver Disease	Digestive System Diseases ;	0.393	0.862
Myasthenia Gravis, Generalized	Nervous System Diseases ; Immune System Diseases ;	0.393	0.862
Myasthenia Gravis, Ocular	Nervous System Diseases ; Immune System Diseases ;	0.393	0.862
Cardiomyopathies	Cardiovascular Diseases ;	0.393	0.862
Autoimmune Lymphoproliferative Syndrome	Hemic and Lymphatic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Immune System Diseases ;	0.393	0.862
Cardiomyopathy, Familial Idiopathic	Cardiovascular Diseases ;	0.393	0.862
Autoimmune Lymphoproliferative Syndrome Type 2B	Hemic and Lymphatic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Immune System Diseases ;	0.393	0.862
Autoimmune Lymphoproliferative Syndrome, Type IA	Hemic and Lymphatic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Immune System Diseases ;	0.393	0.862
Autoimmune Lymphoproliferative Syndrome, Type IB	Hemic and Lymphatic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Immune System Diseases ;	0.393	0.862
Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Recessive	Hemic and Lymphatic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Immune System Diseases ;	0.393	0.862
Acute Myeloid Leukemia (AML-M2)	Neoplasms ;	0.393	0.862
Autoimmune Lymphoproliferative Syndrome Type 1, Autosomal Dominant	Hemic and Lymphatic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Immune System Diseases ;	0.393	0.862
Nonalcoholic Steatohepatitis	Digestive System Diseases ;	0.393	0.862
Male Germ Cell Tumor	Neoplasms ; Male Urogenital Diseases ; Endocrine System Diseases ;	0.393	0.862
NO RESULT FOUND

Description:	Fas (TNF receptor superfamily member 6) [Source:MGI Symbol;Acc:MGI:95484]
Synonyms:	TNFR6, CD95, AI196731, nfrsf6, APT1, lpr, APO1
Other ID(s):	MGI:95484, ENSMUSG00000024778
Protein Accession Numbers:	XP_030106608, XP_011245443, XP_030106611, XP_030106607, NP_032013, XP_030106609, XP_030106606, XP_036017323, NP_001140180
Statistics:	ClinVar(91) gnomAD(206) COSMIC(209) PTM(33)

Classification of Clinicial Significance of ClinVar Data