Fas (GeneID: 14102) | Mus musculus
Description: Fas (TNF receptor superfamily member 6) [Source:MGI Symbol;Acc:MGI:95484]
Synonyms: TNFR6, CD95, AI196731, nfrsf6, APT1, lpr, APO1
Other ID(s): MGI:95484, ENSMUSG00000024778
Protein Accession Numbers: XP_030106608, XP_011245443, XP_030106611, XP_030106607, NP_032013, XP_030106609, XP_030106606, NP_001140180, XP_036017323
Statistics: ClinVar(99) gnomAD(219) COSMIC(207) PTM(33)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000352159 ENST00000355279 ENST00000355740 You are here now! ENST00000357339 ENST00000479522 ENST00000484444 ENST00000488877 ENST00000492756 ENST00000494410 NP_000034 You are here now! NP_001307548 NP_690610 NP_690611


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region 85-127 CL0607 TNF_receptor Homo sapiens
PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region 129-165 CL0607 TNF_receptor Homo sapiens
PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region 85-127 CL0607 TNF_receptor Homo sapiens
PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region 129-165 CL0607 TNF_receptor Homo sapiens
PF00531 Death Death domain 230-314 CL0041 Death Homo sapiens

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Alloxan Diabetes Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.393 0.862
Anemia, Splenic Hemic and Lymphatic Diseases ; 0.393 0.862
Autoimmune Diseases Immune System Diseases ; 0.393 0.862
Behcet Syndrome Stomatognathic Diseases ; Eye Diseases ; Cardiovascular Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Skin and Connective Tissue Diseases ; 0.393 0.862
Malignant neoplasm of urinary bladder Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.393 0.862
Bladder Neoplasm Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.393 0.862
Squamous cell carcinoma Neoplasms ; 0.393 0.862
Cardiomyopathy, Dilated Cardiovascular Diseases ; 0.393 0.862
Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.393 0.862
Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.393 0.862
Hematological Disease Hemic and Lymphatic Diseases ; 0.393 0.862
Hypersplenism Hemic and Lymphatic Diseases ; 0.393 0.862
Leukemia, Myelocytic, Acute Neoplasms ; 0.393 0.862
Lung Neoplasms Neoplasms ; Respiratory Tract Diseases ; 0.393 0.862
Lymphoma, Non-Hodgkin Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.393 0.862
Malaria, Falciparum Parasitic Diseases ; 0.393 0.862
Myasthenia Gravis Nervous System Diseases ; Immune System Diseases ; 0.393 0.862
Acute Myeloid Leukemia, M1 Neoplasms ; 0.393 0.862
Necrosis Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Nephritis Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.393 0.862
Pregnancy Complications, Cardiovascular Female Urogenital Diseases and Pregnancy Complications ; Cardiovascular Diseases ; 0.393 0.862
Cardiomyopathies, Primary Cardiovascular Diseases ; 0.393 0.862
Proteinuria Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Schizophrenia Mental Disorders ; 0.393 0.862
Myocardial Diseases, Secondary Cardiovascular Diseases ; 0.393 0.862
Streptozotocin Diabetes Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.393 0.862
Taste Disorders Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Uveomeningoencephalitic Syndrome Nervous System Diseases ; Eye Diseases ; Immune System Diseases ; 0.393 0.862
Diffuse Large B-Cell Lymphoma Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.393 0.862
Lymphoma, T-Cell, Cutaneous Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.393 0.862
Liver Failure, Acute Digestive System Diseases ; 0.393 0.862
Taste Disorder, Primary Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Taste Disorder, Primary, Sweet Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Taste Disorder, Primary, Salt Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Taste Disorder, Primary, Bitter Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Taste Disorder, Anterior Tongue Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Taste Disorder, Secondary Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Taste Disorder, Secondary, Sweet Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Taste Disorder, Secondary, Salt Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Taste Disorder, Secondary, Bitter Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Taste Disorder, Posterior Tongue Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Taste, Metallic Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.393 0.862
Malignant neoplasm of lung Neoplasms ; Respiratory Tract Diseases ; 0.393 0.862
Acute Lung Injury Respiratory Tract Diseases ; 0.393 0.862
Ventricular Dysfunction, Left Cardiovascular Diseases ; 0.393 0.862
Granulomatous Slack Skin Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.393 0.862
Hematologic Neoplasms Neoplasms ; Hemic and Lymphatic Diseases ; 0.393 0.862
Non-alcoholic Fatty Liver Disease Digestive System Diseases ; 0.393 0.862
Myasthenia Gravis, Generalized Nervous System Diseases ; Immune System Diseases ; 0.393 0.862
Myasthenia Gravis, Ocular Nervous System Diseases ; Immune System Diseases ; 0.393 0.862
Cardiomyopathies Cardiovascular Diseases ; 0.393 0.862
Autoimmune Lymphoproliferative Syndrome Hemic and Lymphatic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Immune System Diseases ; 0.393 0.862
Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases ; 0.393 0.862
Autoimmune Lymphoproliferative Syndrome Type 2B Hemic and Lymphatic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Immune System Diseases ; 0.393 0.862
Autoimmune Lymphoproliferative Syndrome, Type IA Hemic and Lymphatic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Immune System Diseases ; 0.393 0.862
Autoimmune Lymphoproliferative Syndrome, Type IB Hemic and Lymphatic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Immune System Diseases ; 0.393 0.862
Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Recessive Hemic and Lymphatic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Immune System Diseases ; 0.393 0.862
Acute Myeloid Leukemia (AML-M2) Neoplasms ; 0.393 0.862
Autoimmune Lymphoproliferative Syndrome Type 1, Autosomal Dominant Hemic and Lymphatic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Immune System Diseases ; 0.393 0.862
Nonalcoholic Steatohepatitis Digestive System Diseases ; 0.393 0.862
Male Germ Cell Tumor Neoplasms ; Male Urogenital Diseases ; Endocrine System Diseases ; 0.393 0.862
NO RESULT FOUND
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