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<!-- Gene search --> </div> <!-- end of preResult page --> <!-- Modal Structure --> <div id="preResult_help" class="modal modal-fixed-footer"> <div class="modal-content"> <h4>Searching Result and Alignments</h4> <p> When a human gene was assigned to multiple orthologs in other organisms, protein sequences from other organisms with higher levels of sequence identity were displayed in multiple species alignment of orthologs. For example, <i>H3F3A</i> has multiple orthologs in <i>C. elegans</i> which are <i>his-69, his-70, his-71, his-72, his-73, cpar-1, his-74,</i> and <i>F20D6.9</i>. <i>C. elegans</i> his-71 possessing the higher levels of sequence identity with H3F3A among other <i>C. elegans</i> H3F3A orthologs will be displayed when you enter H3F3A. However, you can also enter <i>his-69, his-70, his-72,his-73, cpar-1, his-74, or F20D6.9 </i> genes individually for multiple species alignment with H3F3A. </p> </div> <div class="modal-footer"> <a href="#!" class="modal-action modal-close waves-effect waves-green btn-flat blue white-text">Agree</a> </div> </div> <script type="text/javascript"> $(document).ready(function() { var mouse_radio_buttons = document.getElementsByName("mouse"); var worm_radio_buttons = document.getElementsByName("worm"); document.getElementById('mouse').style.display = 'none'; document.getElementById('worm').style.display = 'none'; for (mouse_radio of mouse_radio_buttons) { mouse_radio.parentNode.style.display = 'none'; }; for (worm_radio of worm_radio_buttons) { worm_radio.parentNode.style.display = 'none'; }; $('.modal').modal(); $("#startAnalyse").addClass("disabled"); $("form :input").change(function() { $("#startAnalyse").addClass("disabled"); var paras = document.getElementsByClassName('alert'); while(paras[0]) { paras[0].parentNode.removeChild(paras[0]); }; speciesList = ['human', 'mouse', 'worm']; selectedSpeciesCount = 0; //must be 3 for the analysis availableSpeciesCount = 0; if($(this).attr('id').startsWith('human')) { for (mouse_radio of mouse_radio_buttons) { mouse_radio.parentNode.style.display = 'none'; mouse_radio.checked = false; }; for (worm_radio of worm_radio_buttons) { worm_radio.parentNode.style.display = 'none'; worm_radio.checked = false; }; } selected_cb = $(this).attr('id'); selected_cb_color = $('label[for=' + selected_cb +']').css('color'); document.getElementById('mouse').style.display = 'block'; document.getElementById('worm').style.display = 'block'; all_radio_buttons = document.getElementsByClassName('convart-radio'); available_mouse = 0; available_worm = 0; selected_first_mouse = true; selected_first_worm = true; first_available_mouse = -1 first_available_worm = -1 for (radio_button of all_radio_buttons) { radio_button_input = $(radio_button.childNodes[0]); radio_button_label = $(radio_button.childNodes[2]); if (radio_button_label.css('color') === selected_cb_color) { radio_button.style.display = 'block'; if(radio_button_input.attr('id').startsWith('mouse')){ if (selected_first_mouse) { first_available_mouse = radio_button_input.attr('id') } selected_first_mouse = false; available_mouse++; } if(radio_button_input.attr('id').startsWith('worm')){ if (selected_first_worm) { first_available_worm = radio_button_input.attr('id') } selected_first_worm = false; available_worm++; } } }; if (available_mouse === 0) { document.getElementById('mouse').insertAdjacentHTML('afterend','<h5 class="alert" >No homolog transcript found for this species.<br><br></h5>'); } if (available_worm === 0) { document.getElementById('worm').insertAdjacentHTML('afterend','<h5 class="alert" >No homolog transcript found for this species.<br><br></h5>'); } if($(this).attr('id').startsWith('human')) { if (first_available_mouse !== -1) { document.getElementById(first_available_mouse).checked = true; } if (first_available_worm !== -1) { document.getElementById(first_available_worm).checked = true; } } $("#startAnalyse").removeClass("disabled"); }); }); // setTimeout(function() { // $("form :input").trigger('change'); // }, 100); </script> <br> <!-- CurrentProject Footer --> <footer class="page-footer"> <div class="container"> <div class="row"> <div class="col l6 s12"> <h5 class="white-text">ConVarT</h5> <p class="grey-text text-lighten-4">The <b>Con</b>served clinical <b>Var</b>iation visualization <b>T</b>ool (ConVarT) is an online visualization resource developed by the Kaplan Lab, with the goal of displaying the evolutionary conservation of amino acid substitutions associated with diseases from ClinVar and gnomAD databases.</p> </div> <div class="col l4 offset-l2 s12"> <h5 class="white-text">Links</h5> <ul> <li><a class="grey-text text-lighten-3" href="https://convart.org/pages/About.php">About</a></li> <li><a class="grey-text text-lighten-3" href="https://convart.org/pages/Help.php">Help</a></li> <li><a class="grey-text text-lighten-3" href="https://convart.org/pages/Faq.php">FAQs</a></li> <li><a class="grey-text text-lighten-3" href="https://convart.org/pages/Contact.php">Contact</a></li> <li><a class="grey-text text-lighten-3" href="https://convart.org/pages/Terms.php">Terms</a></li> </ul> </div> </div> </div> <div class="footer-copyright"> <div class="container"> © 2019 ConVarT <a class="grey-text text-lighten-4 right" href="http://kaplanlab.com">Kaplan Lab</a> </div> </div> </footer> <!-- end of footer --> </body> </html>