MYC (GeneID: 4609) | Homo sapiens
Description: MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553]
Synonyms: MYCC, bHLHe39, MRTL, c-Myc
Other ID(s): HGNC:7553, ENSG00000136997
Protein Accession Numbers: ENST00000259523, NP_001341799, ENST00000517291, ENST00000524013, ENST00000377970, NP_002458, ENST00000520751
Statistics: gnomAD(52)
gnomAD Variants By Annotation

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000259523 ENST00000377970 ENST00000517291 ENST00000520751 ENST00000524013 NP_001341799 NP_002458


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
NO DOMAINS EXIST

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Adenocarcinoma Neoplasms ; 0.382 0.724
Malignant neoplasm of urinary bladder Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.382 0.724
Bladder Neoplasm Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.382 0.724
Burkitt Lymphoma Virus Diseases ; Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.382 0.724
Malignant Neoplasms Neoplasms ; 0.382 0.724
Carcinoma Neoplasms ; 0.382 0.724
Malignant tumor of colon Neoplasms ; Digestive System Diseases ; 0.382 0.724
Adenocarcinoma of prostate N/A 0.382 0.724
Merkel cell carcinoma Virus Diseases ; Neoplasms ; 0.382 0.724
Non-Small Cell Lung Carcinoma Neoplasms ; Respiratory Tract Diseases ; 0.382 0.724
Squamous cell carcinoma Neoplasms ; 0.382 0.724
Hypertrophic Cardiomyopathy Cardiovascular Diseases ; 0.382 0.724
Neoplastic Cell Transformation Neoplasms ; Pathological Conditions, Signs and Symptoms ; 0.382 0.724
Uterine Cervical Neoplasm Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; 0.382 0.724
Cleft upper lip Stomatognathic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.382 0.724
Cleft Palate Musculoskeletal Diseases ; Stomatognathic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.382 0.724
Colonic Neoplasms Neoplasms ; Digestive System Diseases ; 0.382 0.724
Endometrial Neoplasms Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; 0.382 0.724
Fatty Liver Digestive System Diseases ; 0.382 0.724
Glioblastoma Neoplasms ; 0.382 0.724
Hemangiosarcoma Neoplasms ; 0.382 0.724
Hepatoma, Morris Neoplasms ; Digestive System Diseases ; 0.382 0.724
Hepatoma, Novikoff Neoplasms ; Digestive System Diseases ; 0.382 0.724
Chronic Lymphocytic Leukemia Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.382 0.724
Leukemia, Myelocytic, Acute Neoplasms ; 0.382 0.724
Liver Cirrhosis, Experimental Digestive System Diseases ; 0.382 0.724
Liver neoplasms Neoplasms ; Digestive System Diseases ; 0.382 0.724
Liver Neoplasms, Experimental Neoplasms ; Digestive System Diseases ; 0.382 0.724
Lung Neoplasms Neoplasms ; Respiratory Tract Diseases ; 0.382 0.724
Malignant neoplasm of stomach Neoplasms ; Digestive System Diseases ; 0.382 0.724
Medulloblastoma Neoplasms ; 0.382 0.724
Multiple Myeloma Neoplasms ; Cardiovascular Diseases ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.382 0.724
Acute Myeloid Leukemia, M1 Neoplasms ; 0.382 0.724
Neoplasm Metastasis Neoplasms ; Pathological Conditions, Signs and Symptoms ; 0.382 0.724
Neoplasms Neoplasms ; 0.382 0.724
Neuroblastoma Neoplasms ; 0.382 0.724
Osteosarcoma Neoplasms ; 0.382 0.724
Pancreatic Neoplasm Neoplasms ; Digestive System Diseases ; Endocrine System Diseases ; 0.382 0.724
Prostatic Neoplasms Neoplasms ; Male Urogenital Diseases ; 0.382 0.724
Stomach Neoplasms Neoplasms ; Digestive System Diseases ; 0.382 0.724
Lymphoma, Small Noncleaved-Cell Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.382 0.724
Polycystic Kidney, Autosomal Dominant Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.382 0.724
Experimental Hepatoma Neoplasms ; Digestive System Diseases ; 0.382 0.724
Benign Neoplasm Neoplasms ; 0.382 0.724
Left Ventricular Hypertrophy Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ; 0.382 0.724
Adenocarcinoma of lung (disorder) Neoplasms ; Respiratory Tract Diseases ; 0.382 0.724
Adenocarcinoma, Basal Cell Neoplasms ; 0.382 0.724
Adenocarcinoma, Oxyphilic Neoplasms ; 0.382 0.724
Carcinoma, Cribriform Neoplasms ; 0.382 0.724
Carcinoma, Granular Cell Neoplasms ; 0.382 0.724
Adenocarcinoma, Tubular Neoplasms ; 0.382 0.724
Anaplastic carcinoma Neoplasms ; 0.382 0.724
Carcinoma, Spindle-Cell Neoplasms ; 0.382 0.724
Undifferentiated carcinoma Neoplasms ; 0.382 0.724
Carcinomatosis Neoplasms ; 0.382 0.724
Medullomyoblastoma Neoplasms ; 0.382 0.724
Neuroectodermal Tumors Neoplasms ; 0.382 0.724
Disease Exacerbation Pathological Conditions, Signs and Symptoms ; 0.382 0.724
Malignant neoplasm of lung Neoplasms ; Respiratory Tract Diseases ; 0.382 0.724
Childhood Medulloblastoma Neoplasms ; 0.382 0.724
Adult Medulloblastoma Neoplasms ; 0.382 0.724
Chromosome Breaks Pathological Conditions, Signs and Symptoms ; 0.382 0.724
Giant Cell Glioblastoma Neoplasms ; 0.382 0.724
African Burkitt's lymphoma Virus Diseases ; Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.382 0.724
Malignant neoplasm of liver Neoplasms ; Digestive System Diseases ; 0.382 0.724
Malignant neoplasm of pancreas Neoplasms ; Digestive System Diseases ; Endocrine System Diseases ; 0.382 0.724
Malignant neoplasm of prostate Neoplasms ; Male Urogenital Diseases ; 0.382 0.724
Chromosome Breakage Pathological Conditions, Signs and Symptoms ; 0.382 0.724
Endometrial Carcinoma Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; 0.382 0.724
Desmoplastic Medulloblastoma Neoplasms ; 0.382 0.724
Polycystic Kidney, Type 1 Autosomal Dominant Disease Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.382 0.724
ovarian neoplasm Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.382 0.724
Malignant neoplasm of ovary Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.382 0.724
Melanotic medulloblastoma Neoplasms ; 0.382 0.724
Glioblastoma Multiforme Neoplasms ; 0.382 0.724
Hereditary Diffuse Gastric Cancer Neoplasms ; Digestive System Diseases ; 0.382 0.724
Cleft palate, isolated Musculoskeletal Diseases ; Stomatognathic Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.382 0.724
Acute Myeloid Leukemia (AML-M2) Neoplasms ; 0.382 0.724
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.382 0.724
Liver carcinoma Neoplasms ; Digestive System Diseases ; 0.382 0.724
Steatohepatitis Digestive System Diseases ; 0.382 0.724
Hematopoetic Myelodysplasia Hemic and Lymphatic Diseases ; 0.382 0.724
Polycystic kidney disease, type 2 Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.382 0.724
MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases ; 0.382 0.724
cervical cancer Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; 0.382 0.724
NO RESULT FOUND
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