CCND2 (GeneID: 894) | Homo sapiens
Description: cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583]
Synonyms: KIAK0002, MPPH3
Other ID(s): HGNC:1583, ENSG00000118971
Protein Accession Numbers: NP_001750, ENST00000536537, ENST00000261254
Statistics: gnomAD(125)
gnomAD Variants By Annotation

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000261254 ENST00000536537 NP_001750


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF00134 Cyclin_N Cyclin, N-terminal domain 74-201 CL0065 Cyclin Caenorhabditis elegans

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Malignant Neoplasms Neoplasms ; 0.519 0.655
Malignant tumor of colon Neoplasms ; Digestive System Diseases ; 0.519 0.655
Colonic Neoplasms Neoplasms ; Digestive System Diseases ; 0.519 0.655
Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.519 0.655
Fibrosis Pathological Conditions, Signs and Symptoms ; 0.519 0.655
Cardiomegaly Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ; 0.519 0.655
Hydrocephalus Nervous System Diseases ; 0.519 0.655
Leukemia, Myelocytic, Acute Neoplasms ; 0.519 0.655
Lung Neoplasms Neoplasms ; Respiratory Tract Diseases ; 0.519 0.655
Acute Myeloid Leukemia, M1 Neoplasms ; 0.519 0.655
Prostatic Neoplasms Neoplasms ; Male Urogenital Diseases ; 0.519 0.655
Schizophrenia Mental Disorders ; 0.519 0.655
Myocardial Ischemia Cardiovascular Diseases ; 0.519 0.655
Polydactyly Musculoskeletal Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.519 0.655
Malignant neoplasm of lung Neoplasms ; Respiratory Tract Diseases ; 0.519 0.655
Malignant neoplasm of prostate Neoplasms ; Male Urogenital Diseases ; 0.519 0.655
Epileptic encephalopathy N/A 0.519 0.655
Carcinoma of lung N/A 0.519 0.655
ovarian neoplasm Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.519 0.655
Malignant neoplasm of ovary Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.519 0.655
Cardiac Hypertrophy Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ; 0.519 0.655
Cirrhosis Pathological Conditions, Signs and Symptoms ; 0.519 0.655
Megalanecephaly Polymicrogyria-Polydactyly Hydrocephalus Syndrome Musculoskeletal Diseases ; Nervous System Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.519 0.655
Acute Myeloid Leukemia (AML-M2) Neoplasms ; 0.519 0.655
Alcohol Toxicity N/A 0.519 0.655
Malformations of Cortical Development Nervous System Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.519 0.655
Intellectual Disability Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ; Mental Disorders ; 0.519 0.655
MEGALENCEPHALY-POLYMICROGYRIA-POLYDACTYLY-HYDROCEPHALUS SYNDROME 3 N/A 0.519 0.655
NO RESULT FOUND
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