F3 (GeneID: 2152) | Homo sapiens
Description: coagulation factor III, tissue factor [Source:HGNC Symbol;Acc:HGNC:3541]
Synonyms: CD142, TFA, TF
Other ID(s): ENSG00000117525, HGNC:3541
Protein Accession Numbers: ENST00000370207, NP_001984, ENST00000334047, NP_001171567
Statistics: ClinVar(6) gnomAD(193) COSMIC(112) PTM(7)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000334047 ENST00000370207 You are here now! NP_001171567 You are here now! NP_001984


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF01108 Tissue_fac Tissue factor 17-118 CL0159 E-set Homo sapiens
PF09294 Interfer-bind Interferon-alpha/beta receptor, fibronectin type III 138-245 CL0159 E-set Homo sapiens

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Malignant neoplasm of breast Neoplasms ; Skin and Connective Tissue Diseases ; 0.458 0.724
Disseminated Intravascular Coagulation Hemic and Lymphatic Diseases ; 0.458 0.724
Acute Promyelocytic Leukemia Neoplasms ; 0.458 0.724
Liver Cirrhosis Digestive System Diseases ; 0.458 0.724
Nephrotic Syndrome Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.458 0.724
Purpura, Thrombotic Thrombocytopenic Hemic and Lymphatic Diseases ; Pathological Conditions, Signs and Symptoms ; 0.458 0.724
Thrombosis Cardiovascular Diseases ; 0.458 0.724
Venous Thrombosis Cardiovascular Diseases ; 0.458 0.724
Thrombus Cardiovascular Diseases ; 0.458 0.724
Deep Vein Thrombosis Cardiovascular Diseases ; 0.458 0.724
Myocardial Ischemia Cardiovascular Diseases ; 0.458 0.724
Fibrosis, Liver Digestive System Diseases ; 0.458 0.724
Breast Carcinoma Neoplasms ; Skin and Connective Tissue Diseases ; 0.458 0.724
Mammary Neoplasms, Human Neoplasms ; Skin and Connective Tissue Diseases ; 0.458 0.724
Congenital Thrombotic Thrombocytopenic Purpura Hemic and Lymphatic Diseases ; Pathological Conditions, Signs and Symptoms ; 0.458 0.724
Mammary Neoplasms Neoplasms ; Skin and Connective Tissue Diseases ; 0.458 0.724
Familial Thrombotic Thrombocytopenic Purpura Hemic and Lymphatic Diseases ; Pathological Conditions, Signs and Symptoms ; 0.458 0.724
NO RESULT FOUND
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