PPARG (GeneID: 5468) | Homo sapiens
Description: peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236]
Synonyms: PARgamma, CIMT1, PPARG2, NR1C3, PPARG1, GLM1
Other ID(s): ENSG00000132170, HGNC:9236
Protein Accession Numbers: ENST00000397012, NP_001317544, NP_001361193, ENST00000396999, ENST00000438682, NP_001361190, NP_619725, ENST00000287820, ENST00000397023, NP_001341596, NP_001361195, ENST00000397010, ENST00000539812, NP_001361192, ENST00000309576, ENST00000397029, NP_001341599, NP_056953, ENST00000397015, NP_001341595, NP_001361194, ENST00000397000, ENST00000455517, NP_001361191, NP_619726, ENST00000287820.6, ENST00000397026, NP_001341597, NP_005028
Statistics: ClinVar(212)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000287820 ENST00000309576 ENST00000396999 ENST00000397000 ENST00000397010 ENST00000397012 ENST00000397015 ENST00000397023 ENST00000397026 ENST00000397029 ENST00000438682 ENST00000455517 ENST00000539812 NP_001317544 NP_001341595 NP_001341596 NP_001341597 NP_001341599 NP_001361190 NP_001361191 NP_001361192 NP_001361193 NP_001361194 NP_001361195 NP_005028


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
PF00104 Hormone_recep Ligand-binding domain of nuclear hormone receptor 269-456 Mus musculus
PF00105 zf-C4 Zinc finger, C4 type (two domains) 107-175 CL0167 Zn_Beta_Ribbon Mus musculus
PF12577 PPARgamma_N PPAR gamma N-terminal region 1-78 Mus musculus

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Adenocarcinoma Neoplasms ; 0.388 0.828
Alloxan Diabetes Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.388 0.828
Alzheimer's Disease Nervous System Diseases ; Mental Disorders ; 0.388 0.828
Atherosclerosis Cardiovascular Diseases ; 0.388 0.828
Barrett Esophagus Neoplasms ; Digestive System Diseases ; 0.388 0.828
Malignant tumor of colon Neoplasms ; Digestive System Diseases ; 0.388 0.828
Colonic Neoplasms Neoplasms ; Digestive System Diseases ; 0.388 0.828
Colorectal Carcinoma Neoplasms ; Digestive System Diseases ; 0.388 0.828
Colorectal Neoplasms Neoplasms ; Digestive System Diseases ; 0.388 0.828
Crohn Disease Digestive System Diseases ; 0.388 0.828
Presenile dementia Nervous System Diseases ; Mental Disorders ; 0.388 0.828
Diabetes Mellitus Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.388 0.828
Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.388 0.828
Lipoatrophic Diabetes Mellitus Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.388 0.828
Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.388 0.828
Diabetic Nephropathy Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.388 0.828
Glomerulonephritis Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.388 0.828
Nodular glomerulosclerosis Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.388 0.828
Heart failure Cardiovascular Diseases ; 0.388 0.828
Congestive heart failure Cardiovascular Diseases ; 0.388 0.828
Hypertensive disease Cardiovascular Diseases ; 0.388 0.828
Inflammation Pathological Conditions, Signs and Symptoms ; 0.388 0.828
Insulin Resistance Nutritional and Metabolic Diseases ; 0.388 0.828
Ischemia Pathological Conditions, Signs and Symptoms ; 0.388 0.828
Kidney Failure, Acute Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.388 0.828
Left-Sided Heart Failure Cardiovascular Diseases ; 0.388 0.828
Lipoidosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Nutritional and Metabolic Diseases ; 0.388 0.828
Liver neoplasms Neoplasms ; Digestive System Diseases ; 0.388 0.828
Malignant neoplasm of stomach Neoplasms ; Digestive System Diseases ; 0.388 0.828
melanoma Neoplasms ; 0.388 0.828
Metabolic Diseases Nutritional and Metabolic Diseases ; 0.388 0.828
Nerve Degeneration Pathological Conditions, Signs and Symptoms ; 0.388 0.828
Obesity Nutritional and Metabolic Diseases ; Pathological Conditions, Signs and Symptoms ; 0.388 0.828
Degenerative polyarthritis Musculoskeletal Diseases ; 0.388 0.828
Pustulosis of Palms and Soles Skin and Connective Tissue Diseases ; 0.388 0.828
Pancreatic Neoplasm Neoplasms ; Digestive System Diseases ; Endocrine System Diseases ; 0.388 0.828
Psoriasis Skin and Connective Tissue Diseases ; 0.388 0.828
Kidney Failure Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.388 0.828
Reperfusion Injury Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ; 0.388 0.828
Schizophrenia Mental Disorders ; 0.388 0.828
Stomach Neoplasms Neoplasms ; Digestive System Diseases ; 0.388 0.828
Streptozotocin Diabetes Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.388 0.828
Thinness Pathological Conditions, Signs and Symptoms ; 0.388 0.828
Thyroid Neoplasm Neoplasms ; Endocrine System Diseases ; 0.388 0.828
T-Cell Lymphoma Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ; 0.388 0.828
Antiphospholipid Syndrome Immune System Diseases ; 0.388 0.828
Polycystic Kidney, Autosomal Dominant Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.388 0.828
Osteoarthrosis Deformans Musculoskeletal Diseases ; 0.388 0.828
Thyroid Gland Follicular Adenoma Neoplasms ; Endocrine System Diseases ; 0.388 0.828
Crohn's disease of large bowel Digestive System Diseases ; 0.388 0.828
Adenocarcinoma, Basal Cell Neoplasms ; 0.388 0.828
Adenocarcinoma, Oxyphilic Neoplasms ; 0.388 0.828
Carcinoma, Cribriform Neoplasms ; 0.388 0.828
Carcinoma, Granular Cell Neoplasms ; 0.388 0.828
Adenocarcinoma, Tubular Neoplasms ; 0.388 0.828
gliosarcoma Neoplasms ; 0.388 0.828
Familial generalized lipodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Skin and Connective Tissue Diseases ; Nutritional and Metabolic Diseases ; 0.388 0.828
Pituitary-dependent Cushing's disease Nervous System Diseases ; Endocrine System Diseases ; 0.388 0.828
Heart Failure, Right-Sided Cardiovascular Diseases ; 0.388 0.828
Chronobiology Disorders Nervous System Diseases ; 0.388 0.828
Papillary thyroid carcinoma Neoplasms ; Endocrine System Diseases ; 0.388 0.828
Dyslipidemias Nutritional and Metabolic Diseases ; 0.388 0.828
Acute Lung Injury Respiratory Tract Diseases ; 0.388 0.828
Crohn's disease of the ileum Digestive System Diseases ; 0.388 0.828
Familial partial lipodystrophy Skin and Connective Tissue Diseases ; Nutritional and Metabolic Diseases ; 0.388 0.828
Familial Alzheimer Disease (FAD) Nervous System Diseases ; Mental Disorders ; 0.388 0.828
Leukostasis Hemic and Lymphatic Diseases ; 0.388 0.828
Giant Cell Glioblastoma Neoplasms ; 0.388 0.828
Malignant neoplasm of liver Neoplasms ; Digestive System Diseases ; 0.388 0.828
Malignant neoplasm of pancreas Neoplasms ; Digestive System Diseases ; Endocrine System Diseases ; 0.388 0.828
Alzheimer Disease, Late Onset Nervous System Diseases ; Mental Disorders ; 0.388 0.828
Mood Disorders Mental Disorders ; 0.388 0.828
Acute Confusional Senile Dementia Nervous System Diseases ; Mental Disorders ; 0.388 0.828
Thyroid carcinoma Neoplasms ; Endocrine System Diseases ; 0.388 0.828
Dyslipoproteinemias Nutritional and Metabolic Diseases ; 0.388 0.828
Regional enteritis Digestive System Diseases ; 0.388 0.828
Colon Carcinoma N/A 0.388 0.828
Alzheimer's Disease, Focal Onset Nervous System Diseases ; Mental Disorders ; 0.388 0.828
Alzheimer Disease, Early Onset Nervous System Diseases ; Mental Disorders ; 0.388 0.828
Inappropriate ACTH Secretion Syndrome Nervous System Diseases ; Endocrine System Diseases ; 0.388 0.828
Circadian Rhythm Disorders Nervous System Diseases ; 0.388 0.828
Psychogenic Inversion of Circadian Rhythm Nervous System Diseases ; 0.388 0.828
Polycystic Kidney, Type 1 Autosomal Dominant Disease Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.388 0.828
Insulin Sensitivity Nutritional and Metabolic Diseases ; 0.388 0.828
IIeocolitis Digestive System Diseases ; 0.388 0.828
Barrett Epithelium Neoplasms ; Digestive System Diseases ; 0.388 0.828
Colorectal Cancer Neoplasms ; Digestive System Diseases ; 0.388 0.828
Atherogenesis Cardiovascular Diseases ; 0.388 0.828
Renal Insufficiency Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.388 0.828
Acute Kidney Insufficiency Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.388 0.828
Bright Disease Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.388 0.828
Hereditary Diffuse Gastric Cancer Neoplasms ; Digestive System Diseases ; 0.388 0.828
Familial Partial Lipodystrophy, Type 1 Skin and Connective Tissue Diseases ; Nutritional and Metabolic Diseases ; 0.388 0.828
Familial Partial Lipodystrophy, Type 2 Skin and Connective Tissue Diseases ; Nutritional and Metabolic Diseases ; 0.388 0.828
Familial Partial Lipodystrophy, Type 3 Skin and Connective Tissue Diseases ; Nutritional and Metabolic Diseases ; 0.388 0.828
Carotid Intimal Medial Thickness 1 Cardiovascular Diseases ; 0.388 0.828
Myocardial Failure Cardiovascular Diseases ; 0.388 0.828
Heart Decompensation Cardiovascular Diseases ; 0.388 0.828
Liver carcinoma Neoplasms ; Digestive System Diseases ; 0.388 0.828
Acute kidney injury Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.388 0.828
Polycystic kidney disease, type 2 Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.388 0.828
Thyroid cancer, follicular Neoplasms ; 0.388 0.828
NO RESULT FOUND
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