Met (GeneID: 17295) | Mus musculus
Description: met proto-oncogene [Source:MGI Symbol;Acc:MGI:96969]
Synonyms: HGFR, AI838057, HGF, Par4, c-Met
Other ID(s): MGI:96969, ENSMUSG00000009376
Protein Accession Numbers: XP_036021796, XP_006505065, XP_011239345, NP_032617, XP_011239344
Statistics: ClinVar(848)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000318493 ENST00000397752 ENST00000422097 ENST00000436117 ENST00000454623 ENST00000456159 ENST00000539704 NP_000236 NP_001120972 NP_001311330 NP_001311331 You are here now!


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
NO DOMAINS EXIST

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Adenocarcinoma Neoplasms ; 0.405 0.793
Astrocytoma Neoplasms ; 0.405 0.793
Autistic Disorder Mental Disorders ; 0.405 0.793
Malignant Neoplasms Neoplasms ; 0.405 0.793
Carcinoma Neoplasms ; 0.405 0.793
Non-Small Cell Lung Carcinoma Neoplasms ; Respiratory Tract Diseases ; 0.405 0.793
Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.405 0.793
Squamous cell carcinoma Neoplasms ; 0.405 0.793
Cognition Disorders Mental Disorders ; 0.405 0.793
Esophageal Neoplasms Neoplasms ; Digestive System Diseases ; 0.405 0.793
Glioblastoma Neoplasms ; 0.405 0.793
Hepatitis, Chronic Digestive System Diseases ; 0.405 0.793
Hepatoma, Morris Neoplasms ; Digestive System Diseases ; 0.405 0.793
Hepatoma, Novikoff Neoplasms ; Digestive System Diseases ; 0.405 0.793
Leukemia, Myelocytic, Acute Neoplasms ; 0.405 0.793
Liver Neoplasms, Experimental Neoplasms ; Digestive System Diseases ; 0.405 0.793
Lung Neoplasms Neoplasms ; Respiratory Tract Diseases ; 0.405 0.793
Malignant neoplasm of stomach Neoplasms ; Digestive System Diseases ; 0.405 0.793
Acute Myeloid Leukemia, M1 Neoplasms ; 0.405 0.793
Neoplasm Invasiveness Neoplasms ; Pathological Conditions, Signs and Symptoms ; 0.405 0.793
Neoplasm Metastasis Neoplasms ; Pathological Conditions, Signs and Symptoms ; 0.405 0.793
Neuroblastoma Neoplasms ; 0.405 0.793
Osteosarcoma Neoplasms ; 0.405 0.793
Prostatic Neoplasms Neoplasms ; Male Urogenital Diseases ; 0.405 0.793
Schizophrenia Mental Disorders ; 0.405 0.793
Sinusitis Respiratory Tract Diseases ; Otorhinolaryngologic Diseases ; 0.405 0.793
Stomach Neoplasms Neoplasms ; Digestive System Diseases ; 0.405 0.793
Experimental Hepatoma Neoplasms ; Digestive System Diseases ; 0.405 0.793
Chronic Persistent Hepatitis Digestive System Diseases ; 0.405 0.793
Benign neoplasm of stomach N/A 0.405 0.793
Benign neoplasm of adrenal gland N/A 0.405 0.793
Benign neoplasm of aortic body and other paraganglia N/A 0.405 0.793
Carcinoma in situ of stomach N/A 0.405 0.793
Adenocarcinoma, Basal Cell Neoplasms ; 0.405 0.793
Adenocarcinoma, Oxyphilic Neoplasms ; 0.405 0.793
Carcinoma, Cribriform Neoplasms ; 0.405 0.793
Carcinoma, Granular Cell Neoplasms ; 0.405 0.793
Adenocarcinoma, Tubular Neoplasms ; 0.405 0.793
Anaplastic carcinoma Neoplasms ; 0.405 0.793
Carcinoma, Spindle-Cell Neoplasms ; 0.405 0.793
Undifferentiated carcinoma Neoplasms ; 0.405 0.793
Carcinomatosis Neoplasms ; 0.405 0.793
Subependymal Giant Cell Astrocytoma Neoplasms ; 0.405 0.793
Hepatoblastoma Neoplasms ; 0.405 0.793
Malignant neoplasm of lung Neoplasms ; Respiratory Tract Diseases ; 0.405 0.793
Childhood Hepatocellular Carcinoma N/A 0.405 0.793
Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.405 0.793
Juvenile Pilocytic Astrocytoma Neoplasms ; 0.405 0.793
Diffuse Astrocytoma Neoplasms ; 0.405 0.793
Anaplastic astrocytoma Neoplasms ; 0.405 0.793
Protoplasmic astrocytoma Neoplasms ; 0.405 0.793
Gemistocytic astrocytoma Neoplasms ; 0.405 0.793
Fibrillary Astrocytoma Neoplasms ; 0.405 0.793
Pilocytic Astrocytoma Neoplasms ; 0.405 0.793
Giant Cell Glioblastoma Neoplasms ; 0.405 0.793
Childhood Cerebral Astrocytoma Neoplasms ; 0.405 0.793
Malignant Adrenal Medulla Neoplasm N/A 0.405 0.793
Malignant neoplasm of liver Neoplasms ; Digestive System Diseases ; 0.405 0.793
Malignant mesothelioma Neoplasms ; Respiratory Tract Diseases ; 0.405 0.793
Malignant neoplasm of prostate Neoplasms ; Male Urogenital Diseases ; 0.405 0.793
Malignant neoplasm of aortic body and other paraganglia N/A 0.405 0.793
Neoplasm of uncertain or unknown behavior of stomach N/A 0.405 0.793
Chronic active hepatitis Digestive System Diseases ; 0.405 0.793
Cryptogenic Chronic Hepatitis Digestive System Diseases ; 0.405 0.793
Malignant neoplasm of esophagus Neoplasms ; Digestive System Diseases ; 0.405 0.793
Mixed oligoastrocytoma Neoplasms ; 0.405 0.793
Stomach Carcinoma N/A 0.405 0.793
Malignant neoplasm of kidney Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.405 0.793
Cerebral Astrocytoma Neoplasms ; 0.405 0.793
Intracranial Astrocytoma Neoplasms ; 0.405 0.793
Hereditary Papillary Renal Carcinoma N/A 0.405 0.793
ovarian neoplasm Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.405 0.793
Malignant neoplasm of ovary Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ; 0.405 0.793
Squamous cell carcinoma of the head and neck Neoplasms ; 0.405 0.793
Chromophobe Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.405 0.793
Sarcomatoid Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.405 0.793
Collecting Duct Carcinoma of the Kidney Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.405 0.793
Papillary Renal Cell Carcinoma Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.405 0.793
Adenocarcinoma of large intestine N/A 0.405 0.793
Type 1 Papillary Renal Cell Carcinoma N/A 0.405 0.793
Glioblastoma Multiforme Neoplasms ; 0.405 0.793
Grade I Astrocytoma Neoplasms ; 0.405 0.793
Hereditary Diffuse Gastric Cancer Neoplasms ; Digestive System Diseases ; 0.405 0.793
Osteofibrous Dysplasia Musculoskeletal Diseases ; 0.405 0.793
Tibia, Bowing of, with Pseudarthrosis and Pectus Excavatum Musculoskeletal Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Wounds and Injuries ; 0.405 0.793
Copper-Overload Cirrhosis Digestive System Diseases ; Nervous System Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Nutritional and Metabolic Diseases ; 0.405 0.793
Acute Myeloid Leukemia (AML-M2) Neoplasms ; 0.405 0.793
Liver carcinoma Neoplasms ; Digestive System Diseases ; 0.405 0.793
Hepatoblastoma Caused By Somatic Mutation Neoplasms ; Digestive System Diseases ; 0.405 0.793
Papillary renal cell carcinoma, familial Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.405 0.793
Intellectual Disability Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ; Mental Disorders ; 0.405 0.793
DEAFNESS, AUTOSOMAL RECESSIVE 97 N/A 0.405 0.793
OSTEOFIBROUS DYSPLASIA, SUSCEPTIBILITY TO N/A 0.405 0.793
NO RESULT FOUND
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