IGF1 (GeneID: 741055) | Pan troglodytes
Description: insulin like growth factor 1 [Source:VGNC Symbol;Acc:VGNC:5427]
Synonyms:
Other ID(s): ENSPTRG00000024078
Protein Accession Numbers: XP_016779545, XP_001156521, XP_024203792, XP_009424389, XP_001156403, XP_024203791, XP_009424388, XP_001156345
Statistics: ClinVar(8) gnomAD(240) COSMIC(753)
ClinVar Pathogenicity of Variations help

∙ Please click the name of species for the protein accession number used in the alignment.
∙ A p letter used as a pointer to positions of post translational modifications in human.
∙ Protein domains illustrated above belong to Homo sapiens (Human).
∙ ClinVar stacked bar chart represents whole protein isoforms of the gene. Please, check the other protein isoforms of the gene below.
∙ If more than one transcripts below are active (with blue background color), it means all the active transcripts have the same sequence.
ENST00000307046 ENST00000337514 ENST00000392904 You are here now! ENST00000392905 ENST00000424202 ENST00000456098 You are here now! NP_000609 NP_001104753 You are here now! NP_001104754 NP_001104755


import_contactsClinVar Data
Variation ID filter_list Allele ID filter_list RS Number filter_list Variant Type filter_list Record filter_list Alteration filter_list Clinicial Sig. filter_list Last Update filter_list Phenotypes filter_list Cytogenetic filter_list Review Status filter_list RCV Acc.N. filter_list

healinggnomAD
Variant ID filter_list Transcript ID filter_list Alteration filter_list Annotation filter_list Allele C. filter_list Allele N. filter_list Allele F. filter_list rsNumber filter_list Flagsfilter_list Filter filter_list

placePost-translational Modifications (PTMs)
Gene Name filter_list ACC ID filter_list PTM Type filter_list Position filter_list Mod-rsd filter_list Site +/-7 Aa filter_list Mw_kd filter_list Site grpID filter_list

blur_onCatalogue of Somatic Mutations in Cancer (COSMIC)
Gene Name filter_list Transcript ID filter_list Sample name filter_list Primary Site filter_list Primary Histology filter_list Mutation ID filter_list Mutation CDS filter_list Mutation Aa filter_list Mutation Desc. filter_list FATHMM Prediction filter_list FATHMM Score filter_list Mutation Somatic Status filter_list PUBMED PMID filter_list Tumor Origin filter_list Position filter_list

chrome_reader_modedbSNP
Gene ID filter_list Transcript ID filter_list Consequence filter_list Position filter_list HGVSp filter_list Impact filter_list

format_align_centerProtein Domains (PFAM)
Pfam Domain filter_list Domain Name filter_list Description filter_list Positions filter_list Clan filter_list Clan Name filter_list Organism filter_list
NO RESULT FOUND
NO DOMAINS EXIST

view_listList of the diseases from DisGeNET
Disease Name filter_list Disease Category filter_list DSI* filter_list DPI** filter_list
Spontaneous abortion Female Urogenital Diseases and Pregnancy Complications ; 0.355 0.828
Abortion, Tubal Female Urogenital Diseases and Pregnancy Complications ; 0.355 0.828
Acromegaly Musculoskeletal Diseases ; Nervous System Diseases ; Endocrine System Diseases ; 0.355 0.828
Adenoma Neoplasms ; 0.355 0.828
Alloxan Diabetes Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.355 0.828
Alzheimer's Disease Nervous System Diseases ; Mental Disorders ; 0.355 0.828
Autistic Disorder Mental Disorders ; 0.355 0.828
Bipolar Disorder Mental Disorders ; 0.355 0.828
Malignant neoplasm of urinary bladder Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.355 0.828
Bladder Neoplasm Neoplasms ; Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.355 0.828
Metabolic Bone Disorder Musculoskeletal Diseases ; Nutritional and Metabolic Diseases ; 0.355 0.828
Malignant neoplasm of breast Neoplasms ; Skin and Connective Tissue Diseases ; 0.355 0.828
Malignant neoplasm of skin Neoplasms ; Skin and Connective Tissue Diseases ; 0.355 0.828
Cholestasis Digestive System Diseases ; 0.355 0.828
Colitis Digestive System Diseases ; 0.355 0.828
Corneal Diseases Eye Diseases ; 0.355 0.828
Crohn Disease Digestive System Diseases ; 0.355 0.828
Delirium Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ; Mental Disorders ; 0.355 0.828
Presenile dementia Nervous System Diseases ; Mental Disorders ; 0.355 0.828
Demyelinating Diseases Nervous System Diseases ; 0.355 0.828
Demyelination Nervous System Diseases ; 0.355 0.828
Mental Depression Behavior and Behavior Mechanisms ; 0.355 0.828
Depressive disorder Mental Disorders ; 0.355 0.828
Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.355 0.828
Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases ; Endocrine System Diseases ; Immune System Diseases ; 0.355 0.828
Drug toxicity Chemically-Induced Disorders ; 0.355 0.828
Endometriosis Female Urogenital Diseases and Pregnancy Complications ; 0.355 0.828
Cardiomegaly Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Hepatitis, Toxic Digestive System Diseases ; Chemically-Induced Disorders ; 0.355 0.828
Diaphragmatic Hernia Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Hyperalgesia Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Hypertensive disease Cardiovascular Diseases ; 0.355 0.828
Kidney Diseases Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.355 0.828
Kidney Failure, Acute Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.355 0.828
Kidney Failure, Chronic Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.355 0.828
Liver Cirrhosis, Experimental Digestive System Diseases ; 0.355 0.828
Mammary Neoplasms, Experimental Neoplasms ; 0.355 0.828
Muscular Atrophy Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Neoplasm Invasiveness Neoplasms ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Neoplasm Metastasis Neoplasms ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Nerve Degeneration Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Osteogenesis Imperfecta Musculoskeletal Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Skin and Connective Tissue Diseases ; 0.355 0.828
Osteopenia Musculoskeletal Diseases ; Nutritional and Metabolic Diseases ; 0.355 0.828
Peripheral Neuropathy Nervous System Diseases ; 0.355 0.828
Pituitary Adenoma Neoplasms ; Nervous System Diseases ; Endocrine System Diseases ; 0.355 0.828
Pituitary Neoplasms Neoplasms ; Nervous System Diseases ; Endocrine System Diseases ; 0.355 0.828
Prostatic Neoplasms Neoplasms ; Male Urogenital Diseases ; 0.355 0.828
Precocious Puberty Endocrine System Diseases ; 0.355 0.828
Pulmonary Fibrosis Respiratory Tract Diseases ; 0.355 0.828
Skin Neoplasms Neoplasms ; Skin and Connective Tissue Diseases ; 0.355 0.828
Streptozotocin Diabetes Nutritional and Metabolic Diseases ; Endocrine System Diseases ; 0.355 0.828
Adverse reaction to drug Chemically-Induced Disorders ; 0.355 0.828
Alcohol abuse Chemically-Induced Disorders ; Mental Disorders ; 0.355 0.828
Hamman-Rich syndrome Respiratory Tract Diseases ; 0.355 0.828
Myocardial Ischemia Cardiovascular Diseases ; 0.355 0.828
Crohn's disease of large bowel Digestive System Diseases ; 0.355 0.828
Russell-Silver syndrome Musculoskeletal Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; 0.355 0.828
Adenoma, Basal Cell Neoplasms ; 0.355 0.828
Follicular adenoma Neoplasms ; 0.355 0.828
Adenoma, Microcystic Neoplasms ; 0.355 0.828
Adenoma, Monomorphic Neoplasms ; 0.355 0.828
Papillary adenoma Neoplasms ; 0.355 0.828
Adenoma, Trabecular Neoplasms ; 0.355 0.828
Diabetes, Autoimmune Nutritional and Metabolic Diseases ; Endocrine System Diseases ; Immune System Diseases ; 0.355 0.828
Middle Cerebral Artery Syndrome Nervous System Diseases ; Cardiovascular Diseases ; 0.355 0.828
Crohn's disease of the ileum Digestive System Diseases ; 0.355 0.828
Endometrioma Female Urogenital Diseases and Pregnancy Complications ; 0.355 0.828
Neurogenic Muscular Atrophy Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Familial Alzheimer Disease (FAD) Nervous System Diseases ; Mental Disorders ; 0.355 0.828
Brittle diabetes Nutritional and Metabolic Diseases ; Endocrine System Diseases ; Immune System Diseases ; 0.355 0.828
Pituitary carcinoma Neoplasms ; Nervous System Diseases ; Endocrine System Diseases ; 0.355 0.828
Malignant neoplasm of prostate Neoplasms ; Male Urogenital Diseases ; 0.355 0.828
Primary microcephaly N/A 0.355 0.828
Allodynia Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Alzheimer Disease, Late Onset Nervous System Diseases ; Mental Disorders ; 0.355 0.828
Acute Confusional Senile Dementia Nervous System Diseases ; Mental Disorders ; 0.355 0.828
Regional enteritis Digestive System Diseases ; 0.355 0.828
Breast Carcinoma Neoplasms ; Skin and Connective Tissue Diseases ; 0.355 0.828
Middle Cerebral Artery Thrombosis Nervous System Diseases ; Cardiovascular Diseases ; 0.355 0.828
Middle Cerebral Artery Occlusion Nervous System Diseases ; Cardiovascular Diseases ; 0.355 0.828
Infarction, Middle Cerebral Artery Nervous System Diseases ; Cardiovascular Diseases ; 0.355 0.828
Alzheimer's Disease, Focal Onset Nervous System Diseases ; Mental Disorders ; 0.355 0.828
Alzheimer Disease, Early Onset Nervous System Diseases ; Mental Disorders ; 0.355 0.828
Hyperalgesia, Primary Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Hyperalgesia, Secondary Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Tactile Allodynia Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Hyperalgesia, Thermal Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Middle Cerebral Artery Embolus Nervous System Diseases ; Cardiovascular Diseases ; 0.355 0.828
Left Middle Cerebral Artery Infarction Nervous System Diseases ; Cardiovascular Diseases ; 0.355 0.828
Embolic Infarction, Middle Cerebral Artery Nervous System Diseases ; Cardiovascular Diseases ; 0.355 0.828
Thrombotic Infarction, Middle Cerebral Artery Nervous System Diseases ; Cardiovascular Diseases ; 0.355 0.828
Right Middle Cerebral Artery Infarction Nervous System Diseases ; Cardiovascular Diseases ; 0.355 0.828
Diabetic Cardiomyopathies Cardiovascular Diseases ; Endocrine System Diseases ; 0.355 0.828
Drug-Induced Liver Disease Digestive System Diseases ; Chemically-Induced Disorders ; 0.355 0.828
IIeocolitis Digestive System Diseases ; 0.355 0.828
Mammary Neoplasms, Human Neoplasms ; Skin and Connective Tissue Diseases ; 0.355 0.828
Hepatitis, Drug-Induced Digestive System Diseases ; Chemically-Induced Disorders ; 0.355 0.828
Cardiac Hypertrophy Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Mammary Neoplasms Neoplasms ; Skin and Connective Tissue Diseases ; 0.355 0.828
Acute Kidney Insufficiency Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.355 0.828
Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications ; 0.355 0.828
Insulin-Like Growth Factor I Deficiency Otorhinolaryngologic Diseases ; Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Clinically Isolated Syndrome, CNS Demyelinating Nervous System Diseases ; 0.355 0.828
Acute kidney injury Male Urogenital Diseases ; Female Urogenital Diseases and Pregnancy Complications ; 0.355 0.828
Mechanical Allodynia Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; 0.355 0.828
Drug-Induced Acute Liver Injury Digestive System Diseases ; Chemically-Induced Disorders ; 0.355 0.828
Intellectual Disability Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ; Mental Disorders ; 0.355 0.828
Diabetes Mellitus, Ketosis-Prone Nutritional and Metabolic Diseases ; Endocrine System Diseases ; Immune System Diseases ; 0.355 0.828
Chemical and Drug Induced Liver Injury Digestive System Diseases ; Chemically-Induced Disorders ; 0.355 0.828
Chemically-Induced Liver Toxicity Digestive System Diseases ; Chemically-Induced Disorders ; 0.355 0.828
NO RESULT FOUND
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