ConVarT

ClinVar Data

Show entries

Variation ID	Allele ID	RS Number	Variant Type	Record	Alteration	Clinicial Sig.	Last Update	Phenotypes	Cytogenetic	Review Status	RCV Acc.N.

gnomAD

Inframe Deletion

Missense Variant

Splice Region Variant

Stop Gained

Stop Lost

Synonymous Variant

Show entries

Variant ID	Transcript ID	Alteration	Annotation	Allele C.	Allele N.	Allele F.	rsNumber
17-40468846-T-G	ENST00000585517	p.Ter723SerextTer2	Stop Lost	0	0	0	rs757779747
17-40468862-C-T	ENST00000585517	p.Asp718Asn	Missense Variant	0	0	0	rs781470131
17-40468864-A-G	ENST00000585517	p.Ile717Thr	Missense Variant	0	0	0	rs746221967
17-40469200-G-A	ENST00000585517	p.Pro715Leu	Missense Variant	0	0	0	rs1064794957
17-40469205-C-T	ENST00000585517	p.Val713Val	Synonymous Variant	0	0	0	rs768290157
17-40469217-C-T	ENST00000585517	p.Lys709Lys	Synonymous Variant	0	0	0	rs1209266918
17-40469218-T-C	ENST00000585517	p.Lys709Arg	Missense Variant	0	0	0	rs1265717948
17-40469229-G-A	ENST00000585517	p.Tyr705Tyr	Synonymous Variant	0	0	0	rs1448084739
17-40469235-G-C	ENST00000585517	p.Ala703Ala	Synonymous Variant	0	0	0	rs1193045843
17-40469239-G-C	ENST00000585517	p.Ala702Gly	Missense Variant	0	0	0	rs778450270
17-40469240-C-T	ENST00000585517	p.Ala702Thr	Missense Variant	1	31368	0.000032	rs747667389
17-40469241-G-A	ENST00000585517	p.Ser701Ser	Splice Region Variant	0	0	0	rs1173682056
17-40469241-G-T	ENST00000585517	p.Ser701Arg	Missense Variant	0	0	0	rs1173682056
17-40474307-G-A	ENST00000585517	p.Asp698Asp	Synonymous Variant	0	0	0
17-40474310-A-T	ENST00000585517	p.Ala697Ala	Synonymous Variant	1	31410	0.000032	rs200529713
17-40474319-A-T	ENST00000585517	p.His694Gln	Missense Variant	6	31414	0.000191	rs139701269
17-40474341-C-T	ENST00000585517	p.Cys687Tyr	Missense Variant	0	0	0	rs756441740
17-40474351-C-G	ENST00000585517	p.Gly684Arg	Missense Variant	2	31412	0.000064	rs780466766
17-40474352-G-A	ENST00000585517	p.Phe683Phe	Synonymous Variant	5	31410	0.000159	rs373256669
17-40474352-G-C	ENST00000585517	p.Phe683Leu	Missense Variant	0	0	0	rs373256669

Showing 1 to 20 of 313 entries

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Post-translational Modifications (PTMs)

Acetylation

Methylation

Phosphorylation

Sumoylation

Ubiquitination

Show entries

Gene Name	ACC ID	PTM Type	Position	Mod-rsd	Site +/-7 Aa	Mw_kd	Site grpID
STAT3	P40763	Ubiquitination	140	K140-ub	TAAVVTEkQQMLEQH	88.07	964547808
STAT3	P40763	Ubiquitination	153	K153-ub	QHLQDVRkRVQDLEQ	88.07	964547810
STAT3	P40763	Ubiquitination	161	K161-ub	RVQDLEQkMkVVENL	88.07	573763764
STAT3	P40763	Ubiquitination	163	K163-ub	QDLEQkMkVVENLQD	88.07	573763766
STAT3	P40763	Phosphorylation	176	Y176-p	QDDFDFNykTLksQG	88.07	23149150
STAT3	P40763	Ubiquitination	177	K177-ub	DDFDFNykTLksQGD	88.07	12107060
STAT3	P40763	Sumoylation	177	K177-sm	DDFDFNykTLksQGD	88.07	610815020
STAT3	P40763	Ubiquitination	180	K180-ub	DFNykTLksQGDMQD	88.07	10838906
STAT3	P40763	Phosphorylation	181	S181-p	FNykTLksQGDMQDL	88.07	22780061
STAT3	P40763	Phosphorylation	194	S194-p	DLNGNNQsVtRQkMQ	88.07	23149141
STAT3	P40763	Phosphorylation	196	T196-p	NGNNQsVtRQkMQQL	88.07	23149144
STAT3	P40763	Ubiquitination	199	K199-ub	NQsVtRQkMQQLEQM	88.07	21185902
STAT3	P40763	Phosphorylation	236	T236-p	EYVQKTLtDEELADW	88.07	55372163
STAT3	P40763	Ubiquitination	244	K244-ub	DEELADWkRRQQIAC	88.07	21185904
STAT3	P40763	Ubiquitination	283	K283-ub	QTRQQIKkLEELQQk	88.07	573763768
STAT3	P40763	Ubiquitination	290	K290-ub	kLEELQQkVSYkGDP	88.07	964547812
STAT3	P40763	Ubiquitination	294	K294-ub	LQQkVSYkGDPIVQH	88.07	15398224
STAT3	P40763	Ubiquitination	318	K318-ub	ELFRNLMkSAFVVER	88.07	27211101
STAT3	P40763	Ubiquitination	348	K348-ub	TGVQFTTkVRLLVKF	88.07	964547814
STAT3	P40763	Ubiquitination	363	K363-ub	PELNYQLkIkVCIDk	88.07	27211096

Showing 1 to 20 of 68 entries

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Catalogue of Somatic Mutations in Cancer (COSMIC)

Deletion - Frameshift

Deletion - In Frame

Insertion - Frameshift

Insertion - In Frame

Substitution - Coding Silent

Substitution - Missense

Substitution - Nonsense

Unknown

Show entries

Gene Name	Transcript ID	Sample name	Primary Site	Primary Histology	Mutation ID	Mutation CDS	Mutation Aa	Mutation Desc.	FATHMM Prediction	FATHMM Score	Mutation Somatic Status	PUBMED PMID	Tumor Origin	Position
STAT3_ENST00000585517	ENST00000585517	2313545	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	90797501	c.1919A>T	p.Y640F	Substitution - Missense	PATHOGENIC	.96568	Reported in another cancer sample as somatic	PMID: 24947020	NS	640
STAT3_ENST00000585517	ENST00000585517	J32_T	lung	carcinoma	90800060	c.550+210A>C	p.?	Unknown	NEUTRAL	.01278	Confirmed somatic variant	PMID: N/A	NS	0
STAT3_ENST00000585517	ENST00000585517	12a	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	90803064	c.1507C>T	p.Q503*	Substitution - Nonsense	PATHOGENIC	.99437	Variant of unknown origin	PMID: 29262531	primary	503
STAT3_ENST00000585517	ENST00000585517	CPCG0527-F1	prostate	carcinoma	90799095	c.550+230A>C	p.?	Unknown	NEUTRAL	.00392	Confirmed somatic variant	PMID: N/A	primary	0
STAT3_ENST00000585517	ENST00000585517	ATL207	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	90797367	c.1852G>C	p.G618R	Substitution - Missense	PATHOGENIC	.91112	Confirmed somatic variant	PMID: 26437031	NS	618
STAT3_ENST00000585517	ENST00000585517	08-0075-608-Post-transplant	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	90797432	c.1981G>T	p.D661Y	Substitution - Missense	PATHOGENIC	.97191	Reported in another cancer sample as somatic	PMID: 29386642	NS	661
STAT3_ENST00000585517	ENST00000585517	PD11384a	breast	carcinoma	90803019	c.2101+298C>T	p.?	Unknown	NEUTRAL	.02485	Confirmed somatic variant	PMID: N/A	NS	0
STAT3_ENST00000585517	ENST00000585517	P107	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	90800366	c.1847A>G	p.E616G	Substitution - Missense	PATHOGENIC	.90711	Reported in another cancer sample as somatic	PMID: 32187361	primary	616
STAT3_ENST00000585517	ENST00000585517	5-VS054-T1	skin	carcinoma	90804466	c.1521C>T	p.V507=	Substitution - coding silent	PATHOGENIC	.87126	Confirmed somatic variant	PMID: 26950094	NS	507
STAT3_ENST00000585517	ENST00000585517	TCGA-BF-A1PX-01	skin	malignant_melanoma	90800456	c.*86C>T	p.?	Unknown	PATHOGENIC	.97941	Confirmed somatic variant	PMID: N/A	primary	0
STAT3_ENST00000585517	ENST00000585517	5-GE015-T4	skin	carcinoma	90800708	c.1066C>T	p.P356S	Substitution - Missense	PATHOGENIC	.99119	Reported in another cancer sample as somatic	PMID: 26950094	NS	356
STAT3_ENST00000585517	ENST00000585517	CDGLIV0707A0251_T	liver	carcinoma	90801490	c.704_705del	p.L235Hfs*7	Deletion - Frameshift			Confirmed somatic variant	PMID: 25159915	NS	235
STAT3_ENST00000585517	ENST00000585517	P-0011355-T01-IM5	breast	carcinoma	90801544	c.172C>T	p.H58Y	Substitution - Missense	PATHOGENIC	.99368	Confirmed somatic variant	PMID: 28481359	primary	58
STAT3_ENST00000585517	ENST00000585517	PD3192a	salivary_gland	carcinoma	90801399	c.*76C>T	p.?	Unknown	NEUTRAL	.20763	Confirmed somatic variant	PMID: 23778141	primary	0
STAT3_ENST00000585517	ENST00000585517	PD40845j_lo0014	urinary_tract	carcinoma	90798204	c.399A>G	p.T133=	Substitution - coding silent	NEUTRAL	.41849	Reported in another cancer sample as somatic	PMID: 33004514	NS	133
STAT3_ENST00000585517	ENST00000585517	TCGA-WE-A8ZN-06	skin	malignant_melanoma	90802947	c.39G>A	p.R13=	Substitution - coding silent		.68767	Confirmed somatic variant	PMID: N/A	NS	13
STAT3_ENST00000585517	ENST00000585517	CPCG0183-F1	prostate	carcinoma	90800287	c.-5+11016T>C	p.?	Unknown	NEUTRAL	.00302	Confirmed somatic variant	PMID: N/A	NS	0
STAT3_ENST00000585517	ENST00000585517	2011-2328:2012-1336-T	upper_aerodigestive_tract	carcinoma	90798369	c.551-144A>C	p.?	Unknown	NEUTRAL	.00423	Confirmed somatic variant	PMID: 25056374	NS	0
STAT3_ENST00000585517	ENST00000585517	tumor_4147360	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	90799880	c.-4-1934A>T	p.?	Unknown	NEUTRAL	.00212	Confirmed somatic variant	PMID: N/A	primary	0
STAT3_ENST00000585517	ENST00000585517	tumor_4124432	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	90804037	c.-4-11670C>T	p.?	Unknown	NEUTRAL	.00755	Confirmed somatic variant	PMID: N/A	primary	0

Showing 1 to 20 of 579 entries

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dbSNP

Gene ID	Transcript ID	Consequence	Position	HGVSp	Impact

Protein Domains (PFAM)

Pfam Domain	Domain Name	Description	Positions	Clan	Clan Name	Organism
NO RESULT FOUND
PF00017	SH2	SH2 domain	584-674	CL0541	SH2-like	Homo sapiens
PF01017	STAT_alpha	STAT protein, all-alpha domain	145-313			Homo sapiens
PF02864	STAT_bind	STAT protein, DNA binding domain	325-464	CL0073	P53-like	Homo sapiens
PF02865	STAT_int	STAT protein, protein interaction domain	2-120			Homo sapiens

List of the diseases from DisGeNET

Disease Name	Disease Category	DSI*	DPI**
Adenocarcinoma	Neoplasms ;	0.358	0.862
Arthritis, Adjuvant-Induced	Musculoskeletal Diseases ;	0.358	0.862
Atherosclerosis	Cardiovascular Diseases ;	0.358	0.862
Autoimmune Diseases	Immune System Diseases ;	0.358	0.862
Malignant neoplasm of breast	Neoplasms ; Skin and Connective Tissue Diseases ;	0.358	0.862
Carcinoma	Neoplasms ;	0.358	0.862
Malignant tumor of colon	Neoplasms ; Digestive System Diseases ;	0.358	0.862
Non-Small Cell Lung Carcinoma	Neoplasms ; Respiratory Tract Diseases ;	0.358	0.862
Squamous cell carcinoma	Neoplasms ;	0.358	0.862
Neoplastic Cell Transformation	Neoplasms ; Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Brain Ischemia	Nervous System Diseases ; Cardiovascular Diseases ;	0.358	0.862
Uterine Cervical Neoplasm	Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ;	0.358	0.862
Ulcerative Colitis	Digestive System Diseases ;	0.358	0.862
Colonic Neoplasms	Neoplasms ; Digestive System Diseases ;	0.358	0.862
Craniosynostosis	Musculoskeletal Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ;	0.358	0.862
Depressive disorder	Mental Disorders ;	0.358	0.862
Diabetes Mellitus, Insulin-Dependent	Nutritional and Metabolic Diseases ; Endocrine System Diseases ; Immune System Diseases ;	0.358	0.862
Fever	Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Fibrosis	Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Cardiomegaly	Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Hepatitis, Chronic	Digestive System Diseases ;	0.358	0.862
Hepatoma, Morris	Neoplasms ; Digestive System Diseases ;	0.358	0.862
Hepatoma, Novikoff	Neoplasms ; Digestive System Diseases ;	0.358	0.862
Inflammation	Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Leukemia, Myelocytic, Acute	Neoplasms ;	0.358	0.862
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.358	0.862
Leukemia, T-Cell	Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.358	0.862
Adult T-Cell Lymphoma/Leukemia	Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.358	0.862
Liver neoplasms	Neoplasms ; Digestive System Diseases ;	0.358	0.862
Liver Neoplasms, Experimental	Neoplasms ; Digestive System Diseases ;	0.358	0.862
Lymphatic Metastasis	Neoplasms ; Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Malignant neoplasm of stomach	Neoplasms ; Digestive System Diseases ;	0.358	0.862
Animal Mammary Neoplasms	Neoplasms ; Animal Diseases ;	0.358	0.862
Mammary Neoplasms, Experimental	Neoplasms ;	0.358	0.862
Medulloblastoma	Neoplasms ;	0.358	0.862
Memory Disorders	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ;	0.358	0.862
Acute Myeloid Leukemia, M1	Neoplasms ;	0.358	0.862
Neoplasm Metastasis	Neoplasms ; Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Pustulosis of Palms and Soles	Skin and Connective Tissue Diseases ;	0.358	0.862
Pancreatic Neoplasm	Neoplasms ; Digestive System Diseases ; Endocrine System Diseases ;	0.358	0.862
Precancerous Conditions	Neoplasms ;	0.358	0.862
Cardiomyopathies, Primary	Cardiovascular Diseases ;	0.358	0.862
Prostatic Neoplasms	Neoplasms ; Male Urogenital Diseases ;	0.358	0.862
Psoriasis	Skin and Connective Tissue Diseases ;	0.358	0.862
Reperfusion Injury	Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Myocardial Diseases, Secondary	Cardiovascular Diseases ;	0.358	0.862
Stomach Neoplasms	Neoplasms ; Digestive System Diseases ;	0.358	0.862
T-Cell Lymphoma	Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.358	0.862
Experimental Hepatoma	Neoplasms ; Digestive System Diseases ;	0.358	0.862
Juvenile-Onset Still Disease	Musculoskeletal Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ;	0.358	0.862
Chronic Persistent Hepatitis	Digestive System Diseases ;	0.358	0.862
Adenocarcinoma, Basal Cell	Neoplasms ;	0.358	0.862
Adenocarcinoma, Oxyphilic	Neoplasms ;	0.358	0.862
Carcinoma, Cribriform	Neoplasms ;	0.358	0.862
Carcinoma, Granular Cell	Neoplasms ;	0.358	0.862
Adenocarcinoma, Tubular	Neoplasms ;	0.358	0.862
Anaplastic carcinoma	Neoplasms ;	0.358	0.862
Carcinoma, Spindle-Cell	Neoplasms ;	0.358	0.862
Undifferentiated carcinoma	Neoplasms ;	0.358	0.862
Carcinomatosis	Neoplasms ;	0.358	0.862
Diabetes, Autoimmune	Nutritional and Metabolic Diseases ; Endocrine System Diseases ; Immune System Diseases ;	0.358	0.862
Medullomyoblastoma	Neoplasms ;	0.358	0.862
Ki-1+ Anaplastic Large Cell Lymphoma	Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.358	0.862
Memory impairment	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ;	0.358	0.862
Congenital diaphragmatic hernia	Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Middle Cerebral Artery Syndrome	Nervous System Diseases ; Cardiovascular Diseases ;	0.358	0.862
Congenital hernia of foramen of Morgagni	Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Congenital hernia of foramen of Bochdalek	Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Childhood Medulloblastoma	Neoplasms ;	0.358	0.862
Adult Medulloblastoma	Neoplasms ;	0.358	0.862
Condition, Preneoplastic	Neoplasms ;	0.358	0.862
Atrophic	Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Brittle diabetes	Nutritional and Metabolic Diseases ; Endocrine System Diseases ; Immune System Diseases ;	0.358	0.862
Malignant neoplasm of liver	Neoplasms ; Digestive System Diseases ;	0.358	0.862
Malignant neoplasm of pancreas	Neoplasms ; Digestive System Diseases ; Endocrine System Diseases ;	0.358	0.862
Malignant neoplasm of prostate	Neoplasms ; Male Urogenital Diseases ;	0.358	0.862
Hematologic Neoplasms	Neoplasms ; Hemic and Lymphatic Diseases ;	0.358	0.862
Chronic active hepatitis	Digestive System Diseases ;	0.358	0.862
Cryptogenic Chronic Hepatitis	Digestive System Diseases ;	0.358	0.862
Breast Carcinoma	Neoplasms ; Skin and Connective Tissue Diseases ;	0.358	0.862
Middle Cerebral Artery Thrombosis	Nervous System Diseases ; Cardiovascular Diseases ;	0.358	0.862
Middle Cerebral Artery Occlusion	Nervous System Diseases ; Cardiovascular Diseases ;	0.358	0.862
Infarction, Middle Cerebral Artery	Nervous System Diseases ; Cardiovascular Diseases ;	0.358	0.862
Desmoplastic Medulloblastoma	Neoplasms ;	0.358	0.862
Age-Related Memory Disorders	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ;	0.358	0.862
Memory Disorder, Semantic	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ;	0.358	0.862
Memory Disorder, Spatial	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ;	0.358	0.862
Memory Loss	Nervous System Diseases ; Pathological Conditions, Signs and Symptoms ; Behavior and Behavior Mechanisms ;	0.358	0.862
Middle Cerebral Artery Embolus	Nervous System Diseases ; Cardiovascular Diseases ;	0.358	0.862
Left Middle Cerebral Artery Infarction	Nervous System Diseases ; Cardiovascular Diseases ;	0.358	0.862
Embolic Infarction, Middle Cerebral Artery	Nervous System Diseases ; Cardiovascular Diseases ;	0.358	0.862
Thrombotic Infarction, Middle Cerebral Artery	Nervous System Diseases ; Cardiovascular Diseases ;	0.358	0.862
Right Middle Cerebral Artery Infarction	Nervous System Diseases ; Cardiovascular Diseases ;	0.358	0.862
Cardiomyopathies	Cardiovascular Diseases ;	0.358	0.862
Cerebral Ischemia	Nervous System Diseases ; Cardiovascular Diseases ;	0.358	0.862
ovarian neoplasm	Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ;	0.358	0.862
Arthritis, Collagen-Induced	Musculoskeletal Diseases ;	0.358	0.862
Arthritis, Experimental	Musculoskeletal Diseases ;	0.358	0.862
Malignant neoplasm of ovary	Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ; Endocrine System Diseases ;	0.358	0.862
Squamous cell carcinoma of the head and neck	Neoplasms ;	0.358	0.862
Mammary Carcinoma, Animal	Neoplasms ; Animal Diseases ;	0.358	0.862
Mammary Neoplasms, Human	Neoplasms ; Skin and Connective Tissue Diseases ;	0.358	0.862
Melanotic medulloblastoma	Neoplasms ;	0.358	0.862
Cardiac Hypertrophy	Cardiovascular Diseases ; Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Mammary Neoplasms	Neoplasms ; Skin and Connective Tissue Diseases ;	0.358	0.862
Atherogenesis	Cardiovascular Diseases ;	0.358	0.862
Cirrhosis	Pathological Conditions, Signs and Symptoms ;	0.358	0.862
Hereditary Diffuse Gastric Cancer	Neoplasms ; Digestive System Diseases ;	0.358	0.862
DIABETES MELLITUS, PERMANENT NEONATAL	Nutritional and Metabolic Diseases ; Endocrine System Diseases ;	0.358	0.862
Copper-Overload Cirrhosis	Digestive System Diseases ; Nervous System Diseases ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Nutritional and Metabolic Diseases ;	0.358	0.862
Acute Myeloid Leukemia (AML-M2)	Neoplasms ;	0.358	0.862
T-Cell Large Granular Lymphocyte Leukemia	Neoplasms ; Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.358	0.862
Hyper-Immunoglobulin E Syndrome, Autosomal Recessive	Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.358	0.862
Hyper-Immunoglobulin E Syndrome, Autosomal Dominant	Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.358	0.862
Hyper-Ige Recurrent Infection Syndrome, Autosomal Dominant	Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.358	0.862
Juvenile arthritis	Musculoskeletal Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ;	0.358	0.862
Juvenile psoriatic arthritis	Musculoskeletal Diseases ; Skin and Connective Tissue Diseases ; Immune System Diseases ;	0.358	0.862
Diabetes Mellitus, Ketosis-Prone	Nutritional and Metabolic Diseases ; Endocrine System Diseases ; Immune System Diseases ;	0.358	0.862
Job Syndrome	Hemic and Lymphatic Diseases ; Immune System Diseases ;	0.358	0.862
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1	N/A	0.358	0.862
cervical cancer	Neoplasms ; Female Urogenital Diseases and Pregnancy Complications ;	0.358	0.862
Familial M�ni�re disease	N/A	0.358	0.862
NO RESULT FOUND

Description:	signal transducer and activator of transcription 3 (acute-phase response factor) [Source:ZFIN;Acc:ZDB-GENE-980526-68]
Synonyms:	wu:fc15d02, -Stat3, STAT3b2, wu:fl59g06, STAT3b1
Other ID(s):	ZDB-GENE-980526-68, ENSDARG00000022712
Protein Accession Numbers:	XP_005163853, XP_005163850, XP_005163852, NP_571554, XP_021325022, XP_005163851
Statistics:	ClinVar(594) gnomAD(313) COSMIC(579) PTM(68)

Classification of Clinicial Significance of ClinVar Data